Home | Screening data | Screen comparisons | Search for compounds | Structure search

Compound InformationSONAR Target prediction
Name:

ARACHIDONIC ACID

Unique Identifier:SPE01504138
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:
Molecular Weight:272.213 g/mol
X log p:15.756  (online calculus)
Lipinksi Failures2
TPSA17.07
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:2
Rotatable Bond Count:14
Canonical Smiles:CCCCCC=CCC=CCC=CCC=CCCCC(O)=O
Source:widespread in animal tissue
Therapeutics:prostaglandin & leucotriene precursor, stimulates NO biosynthesis
Generic_name:ARACHIDONIC ACID
Chemical_iupac_name:ARACHIDONIC ACID
Drug_type:Experimental
Kegg_compound_id:C00219
Drugbank_id:EXPT00409
Logp:4.881
Cas_registry_number:506-32-1
Drug_category:Prostaglandin H2 Synthase-1 inhibitor
Organisms_affected:-1

Found: 10 active | as graph: single | with analogs << Back 1 2 3 4 5 6 7 8 9 10 Next >> 
Species: 4932
Condition: BEM2
Replicates: 2
Raw OD Value: r im 0.6480±0.021496
Normalized OD Score: sc h 0.7459±0.0370994
Z-Score: -7.4633±0.972377
p-Value: 0.000000000006191
Z-Factor: 0.128281
Fitness Defect: 25.8079
Bioactivity Statement: Active
Experimental Conditions
Library:Spectrum
Plate Number and Position:24|H6
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:27.20 Celcius
Date:2006-03-25 YYYY-MM-DD
Plate CH Control (+):0.04235±0.00174
Plate DMSO Control (-):0.6381749999999999±0.01611
Plate Z-Factor:0.9054
png
ps
pdf

DBLink | Rows returned: 21<< Back 1 2 3 4 Next >> 
5462112 (5E,8E,11E,14E)-icosa-5,8,11,14-tetraenoic acid
6437826 sodium (5E,8E,11E,14E)-icosa-5,8,11,14-tetraenoate
6439516 (5E,8E,14E)-icosa-5,8,14-trienoic acid
6439528 (5E,8E,11E,14E)-19-hydroxyicosa-5,8,11,14-tetraenoic acid
6439722 (5E,8E,11E,14E)-10,10-dimethylicosa-5,8,11,14-tetraenoic acid
6440150 (5E,8E,11E,14E)-7,7-dimethylicosa-5,8,11,14-tetraenoic acid

internal high similarity DBLink | Rows returned: 1
LOPAC 00855 0.9783

active | Cluster 8909 | Additional Members: 3 | Rows returned: 0

Service provided by the Mike Tyers Laboratory