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Compound InformationSONAR Target prediction
Name:

10-HYDROXYCAMPTOTHECIN

Unique Identifier:SPE01504123
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:
Molecular Weight:348.224 g/mol
X log p:9.164  (online calculus)
Lipinksi Failures1
TPSA58.97
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:7
Rotatable Bond Count:1
Canonical Smiles:CCC1(O)C(=O)OCC2C(=O)N3Cc4cc5cc(O)ccc5nc4C3=CC=21
Class:alkaloid
Source:Camptotheca acuminata
Reference:J Med Chem 29:1553 (1986); J Nat Prod 53:186 (1990)
Therapeutics:antineoplastic

Found: 203 nonactive | as graph: single | with analogs [1] << Back 171 172 173 174 175 176 177 178 179 180  Next >> [203]
Species: 4932
Condition: SWE1
Replicates: 2
Raw OD Value: r im 0.7241±0.0133643
Normalized OD Score: sc h 1.0191±0.00885982
Z-Score: 0.6374±0.213439
p-Value: 0.528544
Z-Factor: -2.95006
Fitness Defect: 0.6376
Bioactivity Statement: Nonactive
Experimental Conditions
Library:SPECMTS3
Plate Number and Position:7|B7
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:23.80 Celcius
Date:2008-05-13 YYYY-MM-DD
Plate CH Control (+):0.04085±0.00065
Plate DMSO Control (-):0.696825±0.02372
Plate Z-Factor:0.8660
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DBLink | Rows returned: 2
97226
4330531

internal high similarity DBLink | Rows returned: 2
LOPAC 00814 0.9800
SPE01502232 0.9800

active | Cluster 1530 | Additional Members: 9 | Rows returned: 5
LAT002A02 0
LOPAC 00814 0
SPE01502232 0
Prest102 0
LAT003C09 0

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