| Compound Information | SONAR Target prediction |
| Name: | SIROLIMUS |
| Unique Identifier: | SPE01504008 |
| MolClass: | Checkout models in ver1.5 and ver1.0 |
| Molecular Formula: | C51H79NO13 |
| Molecular Weight: | 834.545 g/mol |
| X log p: | (online calculus) |
| Lipinksi Failures | |
| TPSA | |
| Hydrogen Bond Donor Count: | |
| Hydrogen Bond Acceptors Count: | |
| Rotatable Bond Count: | |
| Canonical Smiles: | COC1CC(CCC1O)CC(C)C1CC(=O)C(C)C=C(C)C(O)C(OC)C(=O)C(C)CC(C)C=CC=CC=C(C )C(CC2CCC(C)C(O)(O2)C(=O)C(=O)N2CCCCC2C(=O)O1)OC |
| Source: | Streptomyces hygroscopicus |
| Therapeutics: | immunosuppressant, antineoplastic; rapamycin |
| Found: 104 active as graph: single | with analogs | [1] << Back 31 32 33 34 35 36 37 38 39 40 Next >> [104] |
| Species: | 4932 |
| Condition: | DIA2 |
| Replicates: | 2 |
| Raw OD Value: r im | 0.0429±0.00205061 |
| Normalized OD Score: sc h | 0.0718±0.00315088 |
| Z-Score: | -42.3000±1.35038 |
| p-Value: | 0 |
| Z-Factor: | 0.891584 |
| Fitness Defect: | INF |
| Bioactivity Statement: | Toxic |
| ps |
| DBLink | Rows returned: 0 |
| internal high similarity DBLink | Rows returned: 0 |
| active | Cluster 4292 | Additional Members: 3 | Rows returned: 1 |
| SPE01503968 | 0.56 |
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