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Compound InformationSONAR Target prediction
Name:

ANISOMYCIN

Unique Identifier:SPE01503906
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:
Molecular Weight:246.154 g/mol
X log p:8.199  (online calculus)
Lipinksi Failures1
TPSA35.53
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:5
Rotatable Bond Count:5
Canonical Smiles:COc1ccc(CC2NCC(O)C2OC(C)=O)cc1
Class:alkaloid
Source:Streptomyces griseolus
Reference:JACS 76:4053 (1954); Chem Pharm Bull 17:1405 (1969); Prog Neurobiology 16:155
(1981); Mol Cell Biochem 14:7352 (1994)
Therapeutics:antiprotozoal, antifungal, protein synthesis inhibitor

Found: 142 active | as graph: single | with analogs [1] << Back 1 2 3 4 5 6 7 8 9 10  Next >> [142]
Species: 4932
Condition: ABP1
Replicates: 2
Raw OD Value: r im 0.5774±0.00311127
Normalized OD Score: sc h 0.8350±0.00531021
Z-Score: -8.4453±0.652112
p-Value: 7.073e-16
Z-Factor: 0.493341
Fitness Defect: 34.8851
Bioactivity Statement: Active
Experimental Conditions
Library:SPECMTS3
Plate Number and Position:7|F6
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:22.30 Celcius
Date:2007-12-20 YYYY-MM-DD
Plate CH Control (+):0.041825±0.00066
Plate DMSO Control (-):0.670175±0.01475
Plate Z-Factor:0.9306
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DBLink | Rows returned: 141 2 3 Next >> 
2199 [4-hydroxy-2-[(4-methoxyphenyl)methyl]pyrrolidin-3-yl] acetate
31549 [(2S,3R,4R)-4-hydroxy-2-[(4-methoxyphenyl)methyl]pyrrolidin-3-yl] acetate
253602 [(2R,3S,4S)-4-hydroxy-2-[(4-methoxyphenyl)methyl]pyrrolidin-3-yl] acetate
462385 [(2S,3R,4R)-4-hydroxy-2-[(4-methoxyphenyl)methyl]pyrrolidin-3-yl] acetate hydrochloride
1268331 [(2R,3R,4R)-4-hydroxy-2-[(4-methoxyphenyl)methyl]pyrrolidin-3-yl] acetate
5458313 [(2S,3R,4R)-4-hydroxy-2-[(4-methoxyphenyl)methyl]pyrrolidin-3-yl] acetate chloride

internal high similarity DBLink | Rows returned: 0

active | Cluster 6951 | Additional Members: 3 | Rows returned: 0
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