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Compound InformationSONAR Target prediction
Name:

URIDINE TRIPHOSPHATE TRISODIUM

Unique Identifier:SPE01503346
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C9H12N2Na3O15P3
Molecular Weight:537.991 g/mol
X log p:-1.178  (online calculus)
Lipinksi Failures1
TPSA224.12
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:17
Rotatable Bond Count:8
Canonical Smiles:[Na+].[Na+].[Na+].[O-]P(O)(=O)OP([O-])(=O)OP([O-])(=O)OCC1OC(C(O)C1O)N
1C=CC(=O)NC1=O
Source:ex yeast
Therapeutics:psychostimulant
Generic_name:URIDINE 5--TRIPHOSPHATE
Chemical_iupac_name:URIDINE 5--TRIPHOSPHATE
Drug_type:Experimental
Kegg_compound_id:C00075
Drugbank_id:EXPT03210
Logp:-5.54 +/- 0.81
Cas_registry_number:63-39-8
Drug_category:tRNA Nucleotidyltransferase inhibitor
Organisms_affected:-1

Found: 114 nonactive as graph: single | with analogs 1 2 3 4 5 6 7 8 9 10  Next >> [114]
Species: 4932
Condition: APC9
Replicates: 2
Raw OD Value: r im 0.7091±0.000989949
Normalized OD Score: sc h 1.0003±0.00492431
Z-Score: 0.0200±0.26782
p-Value: 0.849826
Z-Factor: -47.7329
Fitness Defect: 0.1627
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Spectrum
Plate Number and Position:13|F5
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:23.20 Celcius
Date:2007-11-22 YYYY-MM-DD
Plate CH Control (+):0.041475±0.00153
Plate DMSO Control (-):0.68835±0.02131
Plate Z-Factor:0.9201
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DBLink | Rows returned: 131 2 3 Next >> 
1181 [[[5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphor
yl]oxyphosphonic acid
5644 1-[3,4-dihydroxy-5-[[[(hydroxy-oxido-phosphoryl)oxy-oxido-phosphoryl]oxy-oxido-phosphoryl]oxymethyl]oxol
an-2-yl]pyrimidine-2,4-dione
6133 [[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hy
droxy-phosphoryl]oxyphosphonic acid
85706 tetrasodium
1-[3,4-dihydroxy-5-[[oxido-(oxido-phosphonatooxy-phosphoryl)oxy-phosphoryl]oxymethyl]oxolan-2-yl]pyrimid
ine-2,4-dione
88265 trisodium
1-[(2R,3R,4R,5R)-3,4-dihydroxy-5-[[[(hydroxy-oxido-phosphoryl)oxy-oxido-phosphoryl]oxy-oxido-phosphoryl]
oxymethyl]oxolan-2-yl]pyrimidine-2,4-dione
151607 [[[(2R,3R,4S,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hy
droxy-phosphoryl]oxyphosphonic acid

internal high similarity DBLink | Rows returned: 1
LOPAC 01281 0.9706

active | Cluster 7710 | Additional Members: 3 | Rows returned: 0
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