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Compound InformationSONAR Target prediction
Name:

FIPEXIDE HYDROCHLORIDE

Unique Identifier:SPE01503222
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C20Cl2H22N2O4
Molecular Weight:403.13 g/mol
X log p:16.306  (online calculus)
Lipinksi Failures1
TPSA51.24
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:6
Rotatable Bond Count:6
Canonical Smiles:Cl.Clc1ccc(OCC(=O)N2CCN(CC2)Cc2ccc3OCOc3c2)cc1
Therapeutics:psychostimulant

Found: 18 active | as graph: single | with analogs << Back 11 12 13 14 15 16 17 18 Next >> 
Species: 4932
Condition: SAM2
Replicates: 2
Raw OD Value: r im 0.5762±0.0148492
Normalized OD Score: sc h 0.9085±0.00176822
Z-Score: -4.6391±0.167489
p-Value: 0.00000406152
Z-Factor: -0.0502056
Fitness Defect: 12.414
Bioactivity Statement: Active
Experimental Conditions
Library:Spectrum
Plate Number and Position:13|H4
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:25.60 Celcius
Date:2007-09-21 YYYY-MM-DD
Plate CH Control (+):0.040475±0.00097
Plate DMSO Control (-):0.6395±0.01909
Plate Z-Factor:0.9476
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DBLink | Rows returned: 3
3351 1-[4-(benzo[1,3]dioxol-5-ylmethyl)piperazin-1-yl]-2-(4-chlorophenoxy)ethanone
161803 1-[4-(benzo[1,3]dioxol-5-ylmethyl)piperazin-1-yl]-2-(4-chlorophenoxy)ethanone hydrochloride
6957679 1-[4-(benzo[1,3]dioxol-5-ylmethyl)-2,3,5,6-tetrahydropyrazin-1-yl]-2-(4-chlorophenoxy)ethanone

internal high similarity DBLink | Rows returned: 0

nonactive | Cluster 5376 | Additional Members: 64 | Rows returned: 2
Prest601 0.405797101449275
HTS 03696 0.367647058823529

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