Home | Screening data | Screen comparisons | Search for compounds | Structure search

Compound InformationSONAR Target prediction
Name:

GLUTATHIONE

Unique Identifier:SPE01502248
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:
Molecular Weight:290.19 g/mol
X log p:-2.978  (online calculus)
Lipinksi Failures1
TPSA68.28
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:9
Rotatable Bond Count:11
Canonical Smiles:NC(CCC(=O)NC(CS)C(=O)NCC(O)=O)C(O)=O
Class:amino acid
Source:plant and animal tissue
Reference:Pharm Biol 11: 539 (1968)
Therapeutics:antioxidant
Generic_name:GLUTHATHIONE
Chemical_iupac_name:GLUTHATHIONE
Drug_type:Experimental
Drugbank_id:EXPT01650
Logp:-0.87 +/- 0.74
Drug_category:Hematopoietic Prostagladin D Synthase inhibitor
Organisms_affected:-1

Found: 205 nonactive as graph: single | with analogs [1] << Back 161 162 163 164 165 166 167 168 169 170  Next >> [205]
Species: 4932
Condition: RIC1
Replicates: 2
Raw OD Value: r im 0.4184±0.0167584
Normalized OD Score: sc h 0.9812±0.0066728
Z-Score: -0.2387±0.123499
p-Value: 0.812048
Z-Factor: -4.52603
Fitness Defect: 0.2082
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Spectrum
Plate Number and Position:10|H11
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:26.70 Celcius
Date:2006-03-17 YYYY-MM-DD
Plate CH Control (+):0.0393±0.00159
Plate DMSO Control (-):0.410775±0.01287
Plate Z-Factor:0.8883
png
ps
pdf

DBLink | Rows returned: 15<< Back 1 2 3 Next >> 
446684 [(2R)-2-[[(4S)-4-amino-4-carboxy-butanoyl]amino]-2-(carboxymethylcarbamoyl)ethyl]sulfanium
448041 2-amino-4-[[(1R)-1-(carboxymethylcarbamoyl)-2-sulfanyl-ethyl]carbamoyl]butanoic acid
448106 (2R)-2-[[(4S)-4-amino-4-carboxy-butanoyl]amino]-2-(carboxymethylcarbamoyl)ethanethiolate
3000793 2-amino-4-[[1-(carboxymethylcarbamoyl)-2-sulfanyl-ethyl]carbamoyl]butanoic acid
3014272 2-[(4-amino-4-carboxy-butanoyl)amino]-2-(carboxymethylcarbamoyl)ethanethiolate; mercury(+2) cation
3081751 2-amino-4-[[1-(carboxylatomethylcarbamoyl)-2-sulfido-ethyl]carbamoyl]butanoate; azane; hydrogen(+1)
cation; platinum(+2) cation; chloride

internal high similarity DBLink | Rows returned: 0

active | Cluster 33 | Additional Members: 4 | Rows returned: 0
Service provided by the Mike Tyers Laboratory