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Compound InformationSONAR Target prediction
Name:

CAMPTOTHECIN

Unique Identifier:SPE01502232
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:
Molecular Weight:332.225 g/mol
X log p:11.182  (online calculus)
Lipinksi Failures1
TPSA58.97
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:6
Rotatable Bond Count:1
Canonical Smiles:CCC1(O)C(=O)OCC2C(=O)N3Cc4cc5ccccc5nc4C3=CC=21
Class:alkaloid
Source:Camptotheca acuminata
Reference:J Am Chem Soc 88: 3888 (1966)
Therapeutics:antineoplastic

Found: 376 active | as graph: single | with analogs [1] << Back 91 92 93 94 95 96 97 98 99 100  Next >> [376]
Species: 4932
Condition: SPE00330001
Replicates: 2
Raw OD Value: r im 0.3973±0.0365574
Normalized OD Score: sc h 0.7910±0.00357296
Z-Score: -4.8975±0.596021
p-Value: 0.00000385454
Z-Factor: -0.131425
Fitness Defect: 12.4663
Bioactivity Statement: Active
Experimental Conditions
Library:SpectrumTMP
Plate Number and Position:2|H9
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:22.40 Celcius
Date:2006-12-21 YYYY-MM-DD
Plate CH Control (+):0.040749999999999995±0.00244
Plate DMSO Control (-):0.519725±0.05098
Plate Z-Factor:0.6296
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DBLink | Rows returned: 5
2538
24360
32939
153546
184196

internal high similarity DBLink | Rows returned: 2
SPE01504123 0.9800
LOPAC 00814 1.0000

nonactive | Cluster 1530 | Additional Members: 9 | Rows returned: 6
SPE01505821 0.535714285714286
SPE01504123 0.178082191780822
LAT002A02 0
LOPAC 00814 0
Prest102 0
LAT003C09 0

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