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Compound InformationSONAR Target prediction
Name:

CAMPTOTHECIN

Unique Identifier:SPE01502232
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:
Molecular Weight:332.225 g/mol
X log p:11.182  (online calculus)
Lipinksi Failures1
TPSA58.97
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:6
Rotatable Bond Count:1
Canonical Smiles:CCC1(O)C(=O)OCC2C(=O)N3Cc4cc5ccccc5nc4C3=CC=21
Class:alkaloid
Source:Camptotheca acuminata
Reference:J Am Chem Soc 88: 3888 (1966)
Therapeutics:antineoplastic

Found: 376 active | as graph: single | with analogs [1] << Back 341 342 343 344 345 346 347 348 349 350  Next >> [376]
Species: 4932
Condition: SPT3
Replicates: 2
Raw OD Value: r im 0.1348±0.00452548
Normalized OD Score: sc h 0.2844±0.00529291
Z-Score: -11.8178±0.523106
p-Value: 1.20447e-30
Z-Factor: 0.806
Fitness Defect: 68.8915
Bioactivity Statement: Active
Experimental Conditions
Library:SPECMTS3
Plate Number and Position:14|A9
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:25.90 Celcius
Date:2008-02-13 YYYY-MM-DD
Plate CH Control (+):0.040975±0.00162
Plate DMSO Control (-):0.46367500000000006±0.01906
Plate Z-Factor:0.8492
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DBLink | Rows returned: 5
2538
24360
32939
153546
184196

internal high similarity DBLink | Rows returned: 2
SPE01504123 0.9800
LOPAC 00814 1.0000

active | Cluster 1530 | Additional Members: 9 | Rows returned: 5
SPE01504123 0.178082191780822
LAT002A02 0
LOPAC 00814 0
Prest102 0
LAT003C09 0

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