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Compound InformationSONAR Target prediction
Name:

Ng-METHYL-L-ARGININE ACETATE

Unique Identifier:SPE01502194
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C9H20N4O4
Molecular Weight:228.121 g/mol
X log p:-1.982  (online calculus)
Lipinksi Failures0
TPSA17.07
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:6
Rotatable Bond Count:7
Canonical Smiles:CNC(=N)NCCCC(N)C(O)=O.CC(O)=O
Reference:Biochem Biophys Res Comm 177: 828 (1991)
Therapeutics:NO synthesis inhibitor
Generic_name:ADMA
Chemical_iupac_name:NG,NG-DIMETHYL-L-ARGININE
Drug_type:Experimental
Kegg_compound_id:C03626
Drugbank_id:EXPT01101
Logp:-3.164
Cas_registry_number:102783-24-4
Drug_category:Nitric Oxide Synthase inhibitor
Organisms_affected:-1

Found: 101 nonactive as graph: single | with analogs [1] << Back 1 2 3 4 5 6 7 8 9 10  Next >> [101]
Species: 4932
Condition: BNI1
Replicates: 2
Raw OD Value: r im 0.7000±0.0161927
Normalized OD Score: sc h 1.0118±0.0203789
Z-Score: 0.5974±1.02506
p-Value: 0.542356
Z-Factor: -10.1142
Fitness Defect: 0.6118
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Spectrum
Plate Number and Position:23|C10
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:26.00 Celcius
Date:2007-09-14 YYYY-MM-DD
Plate CH Control (+):0.0429±0.00220
Plate DMSO Control (-):0.6773750000000001±0.01899
Plate Z-Factor:0.9120
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DBLink | Rows returned: 0

internal high similarity DBLink | Rows returned: 4
LOPAC 00409 0.9057
RH 01444 0.9057
LOPAC 00422 1.0000
LOPAC 00447 1.0000

active | Cluster 4071 | Additional Members: 12 | Rows returned: 0

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