Compound Information | SONAR Target prediction | Name: | 1-AMINOCYCLOBUTANE CARBOXYLIC ACID | Unique Identifier: | SPE01502131 | MolClass: | Checkout models in ver1.5 and ver1.0 | Molecular Formula: | C5H9NO2 | Molecular Weight: | 106.059 g/mol | X log p: | -2.117 (online calculus) | Lipinksi Failures | 0 | TPSA | 17.07 | Hydrogen Bond Donor Count: | 0 | Hydrogen Bond Acceptors Count: | 3 | Rotatable Bond Count: | 1 | Canonical Smiles: | NC1(CCC1)C(O)=O | Source: | (ACBC) | Reference: | Eur J Pharmacol 161: 281 (1989) | Therapeutics: | NMDA receptor antagonist | Generic_name: | 2-METHYLLEUCINE | Chemical_iupac_name: | 2-METHYLLEUCINE | Drug_type: | Experimental | Drugbank_id: | EXPT00130 | Drug_category: | Branched-Chain Amino Acid Aminotransferase inhibitor | Organisms_affected: | -1 |
Species: |
4932 |
Condition: |
CDC73 |
Replicates: |
2 |
Raw OD Value: r im |
0.3075±0.0309006 |
Normalized OD Score: sc h |
0.7322±0.024059 |
Z-Score: |
-6.7387±0.252344 |
p-Value: |
0.000000000029159 |
Z-Factor: |
-0.311325 |
Fitness Defect: |
24.2583 |
Bioactivity Statement: |
Active |
Experimental Conditions | | Library: | Spectrum | Plate Number and Position: | 23|F9 | Drug Concentration: | 50.00 nM | OD Absorbance: | 600 nm | Robot Temperature: | 26.90 Celcius | Date: | 2007-09-19 YYYY-MM-DD | Plate CH Control (+): | 0.0399±0.00093 | Plate DMSO Control (-): | 0.413125±0.03504 | Plate Z-Factor: | 0.6734 |
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176425 |
(2R)-2-amino-4-methyl-pentanoic acid |
194032 |
(2S)-2-amino-4,4-dimethyl-pentanoic acid |
229526 |
2-amino-2-methyl-pentanoic acid |
236508 |
2-amino-2-cyclopropyl-propanoic acid |
272725 |
2-amino-3,4-dimethyl-pentanoic acid |
314104 |
2-amino-3,4,4-trimethyl-pentanoic acid |
internal high similarity DBLink | Rows returned: 0 | |
active | Cluster 4858 | Additional Members: 8 | Rows returned: 0 | |
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