| Compound Information | SONAR Target prediction | | Name: | 1-AMINOCYCLOBUTANE CARBOXYLIC ACID | | Unique Identifier: | SPE01502131 | | MolClass: | Checkout models in ver1.5 and ver1.0 | | Molecular Formula: | C5H9NO2 | | Molecular Weight: | 106.059 g/mol | | X log p: | -2.117 (online calculus) | | Lipinksi Failures | 0 | | TPSA | 17.07 | | Hydrogen Bond Donor Count: | 0 | | Hydrogen Bond Acceptors Count: | 3 | | Rotatable Bond Count: | 1 | | Canonical Smiles: | NC1(CCC1)C(O)=O | | Source: | (ACBC) | | Reference: | Eur J Pharmacol 161: 281 (1989) | | Therapeutics: | NMDA receptor antagonist | | Generic_name: | 2-METHYLLEUCINE | | Chemical_iupac_name: | 2-METHYLLEUCINE | | Drug_type: | Experimental | | Drugbank_id: | EXPT00130 | | Drug_category: | Branched-Chain Amino Acid Aminotransferase inhibitor | | Organisms_affected: | -1 |
| Species: |
4932 |
| Condition: |
SMI1 |
| Replicates: |
2 |
| Raw OD Value: r im |
0.4385±0.0809637 |
| Normalized OD Score: sc h |
0.7165±0.0940282 |
| Z-Score: |
-5.8938±1.47509 |
| p-Value: |
0.000000615028 |
| Z-Factor: |
-0.247608 |
| Fitness Defect: |
14.3016 |
| Bioactivity Statement: |
Active |
| Experimental Conditions | | | Library: | Spectrum | | Plate Number and Position: | 23|F9 | | Drug Concentration: | 50.00 nM | | OD Absorbance: | 600 nm | | Robot Temperature: | 27.10 Celcius | | Date: | 2005-12-20 YYYY-MM-DD | | Plate CH Control (+): | 0.038599999999999995±0.00238 | | Plate DMSO Control (-): | 0.620525±0.01476 | | Plate Z-Factor: | 0.9154 |
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| 176425 |
(2R)-2-amino-4-methyl-pentanoic acid |
| 194032 |
(2S)-2-amino-4,4-dimethyl-pentanoic acid |
| 229526 |
2-amino-2-methyl-pentanoic acid |
| 236508 |
2-amino-2-cyclopropyl-propanoic acid |
| 272725 |
2-amino-3,4-dimethyl-pentanoic acid |
| 314104 |
2-amino-3,4,4-trimethyl-pentanoic acid |
| internal high similarity DBLink | Rows returned: 0 | |
| active | Cluster 4858 | Additional Members: 8 | Rows returned: 0 | |
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