| Compound Information | SONAR Target prediction |
| Name: | 1-AMINOCYCLOBUTANE CARBOXYLIC ACID |
| Unique Identifier: | SPE01502131 |
| MolClass: | Checkout models in ver1.5 and ver1.0 |
| Molecular Formula: | C5H9NO2 |
| Molecular Weight: | 106.059 g/mol |
| X log p: | -2.117 (online calculus) |
| Lipinksi Failures | 0 |
| TPSA | 17.07 |
| Hydrogen Bond Donor Count: | 0 |
| Hydrogen Bond Acceptors Count: | 3 |
| Rotatable Bond Count: | 1 |
| Canonical Smiles: | NC1(CCC1)C(O)=O |
| Source: | (ACBC) |
| Reference: | Eur J Pharmacol 161: 281 (1989) |
| Therapeutics: | NMDA receptor antagonist |
| Generic_name: | 2-METHYLLEUCINE |
| Chemical_iupac_name: | 2-METHYLLEUCINE |
| Drug_type: | Experimental |
| Drugbank_id: | EXPT00130 |
| Drug_category: | Branched-Chain Amino Acid Aminotransferase inhibitor |
| Organisms_affected: | -1 |
| Found: 4 active | as graph: single | with analogs | 1 2 3 4 Next >> |
| Species: | 4932 |
| Condition: | CDC73 |
| Replicates: | 2 |
| Raw OD Value: r im | 0.3075±0.0309006 |
| Normalized OD Score: sc h | 0.7322±0.024059 |
| Z-Score: | -6.7387±0.252344 |
| p-Value: | 0.000000000029159 |
| Z-Factor: | -0.311325 |
| Fitness Defect: | 24.2583 |
| Bioactivity Statement: | Active |
| ps |
| DBLink | Rows returned: 87 | << Back 1 2 3 4 5 6 7 8 9 10 Next >> |
| 65098 | (2S)-2-aminopentanoic acid |
| 76551 | (2R,3R)-2-amino-3-methyl-pentanoic acid |
| 89643 | 1-aminocyclobutane-1-carboxylic acid |
| 94206 | (2R,3S)-2-amino-3-methyl-pentanoic acid |
| 95515 | 2-amino-2,4-dimethyl-pentanoic acid |
| 99288 | (2S,3R)-2-amino-3-methyl-pentanoic acid |
| internal high similarity DBLink | Rows returned: 0 |
| nonactive | Cluster 4858 | Additional Members: 8 | Rows returned: 6 |
| LOPAC 00333 | 0.368421052631579 |
| SPE01502128 | 0.294117647058823 |
| LAT003D03 | 0 |
| LAT003A06 | 0 |
| SPE01502130 | 0 |
| LOPAC 00644 | 0 |
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