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Compound InformationSONAR Target prediction
Name:

1-AMINOCYCLOBUTANE CARBOXYLIC ACID

Unique Identifier:SPE01502131
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C5H9NO2
Molecular Weight:106.059 g/mol
X log p:-2.117  (online calculus)
Lipinksi Failures0
TPSA17.07
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:3
Rotatable Bond Count:1
Canonical Smiles:NC1(CCC1)C(O)=O
Source:(ACBC)
Reference:Eur J Pharmacol 161: 281 (1989)
Therapeutics:NMDA receptor antagonist
Generic_name:2-METHYLLEUCINE
Chemical_iupac_name:2-METHYLLEUCINE
Drug_type:Experimental
Drugbank_id:EXPT00130
Drug_category:Branched-Chain Amino Acid Aminotransferase inhibitor
Organisms_affected:-1

Found: 4 active | as graph: single | with analogs << Back 1 2 3 4 Next >> 
Species: 4932
Condition: MCK1
Replicates: 2
Raw OD Value: r im 0.5102±0.00438406
Normalized OD Score: sc h 0.8942±0.00914744
Z-Score: -4.5172±0.741809
p-Value: 0.0000328994
Z-Factor: -1.39211
Fitness Defect: 10.3221
Bioactivity Statement: Active
Experimental Conditions
Library:Spectrum
Plate Number and Position:23|F9
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:25.80 Celcius
Date:2007-11-13 YYYY-MM-DD
Plate CH Control (+):0.039749999999999994±0.00178
Plate DMSO Control (-):0.57205±0.03761
Plate Z-Factor:0.7665
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DBLink | Rows returned: 87<< Back 11 12 13 14 15 Next >> 
5460911 (2S,3S)-2-amino-3-methyl-pentanoate
6334464 sodium; 2-azanidyl-4-methyl-pentanoate; germanium
6369563 2-amino-4-methyl-pentanoic acid; tin
6372000 germanium; (3-methyl-1-oxoniocarbonyl-butyl)azanide
6394833 copper oxidanium 2-amino-3-methyl-pentanoic acid
6711700 2-azanidyl-4-methyl-pentanoate; germanium

internal high similarity DBLink | Rows returned: 0

active | Cluster 4858 | Additional Members: 8 | Rows returned: 0
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