Compound Information | SONAR Target prediction | Name: | CYCLOLEUCINE | Unique Identifier: | SPE01502128 | MolClass: | Checkout models in ver1.5 and ver1.0 | Molecular Formula: | | Molecular Weight: | 118.07 g/mol | X log p: | -2.117 (online calculus) | Lipinksi Failures | 0 | TPSA | 17.07 | Hydrogen Bond Donor Count: | 0 | Hydrogen Bond Acceptors Count: | 3 | Rotatable Bond Count: | 1 | Canonical Smiles: | NC1(CCCC1)C(O)=O | Source: | synthetic | Therapeutics: | NMDA receptor antagonist (gly) | Generic_name: | NORLEUCINE | Chemical_iupac_name: | NORLEUCINE | Drug_type: | Experimental | Drugbank_id: | EXPT02355 | Drug_category: | Phenylalanine-4-Hydroxylase inhibitor | Organisms_affected: | -1 |
Species: |
4932 |
Condition: |
AAT2 |
Replicates: |
2 |
Raw OD Value: r im |
0.7479±0.0119501 |
Normalized OD Score: sc h |
1.0180±0.00137791 |
Z-Score: |
0.9529±0.0524906 |
p-Value: |
0.340984 |
Z-Factor: |
-2.58694 |
Fitness Defect: |
1.0759 |
Bioactivity Statement: |
Nonactive |
Experimental Conditions | | Library: | SPECMTS3 | Plate Number and Position: | 1|C4 | Drug Concentration: | 50.00 nM | OD Absorbance: | 600 nm | Robot Temperature: | 23.30 Celcius | Date: | 2008-04-08 YYYY-MM-DD | Plate CH Control (+): | 0.039975±0.00102 | Plate DMSO Control (-): | 0.7103±0.01415 | Plate Z-Factor: | 0.9224 |
| png ps pdf |
6991974 |
(2S)-2-azaniumylhexanoate |
6999776 |
(2R)-2-azaniumylhexanoate |
9209420 |
(2R)-2-azaniumyl-3-cyclopropyl-propanoate |
9209421 |
(2R)-2-amino-3-cyclopropyl-propanoic acid |
15605587 |
(2S)-2-amino-2,5,5-trimethyl-hexanoic acid |
internal high similarity DBLink | Rows returned: 5 | |
active | Cluster 4858 | Additional Members: 8 | Rows returned: 1 | |
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