| Compound Information | SONAR Target prediction | | Name: | CYCLOLEUCINE | | Unique Identifier: | SPE01502128 | | MolClass: | Checkout models in ver1.5 and ver1.0 | | Molecular Formula: | | | Molecular Weight: | 118.07 g/mol | | X log p: | -2.117 (online calculus) | | Lipinksi Failures | 0 | | TPSA | 17.07 | | Hydrogen Bond Donor Count: | 0 | | Hydrogen Bond Acceptors Count: | 3 | | Rotatable Bond Count: | 1 | | Canonical Smiles: | NC1(CCCC1)C(O)=O | | Source: | synthetic | | Therapeutics: | NMDA receptor antagonist (gly) | | Generic_name: | NORLEUCINE | | Chemical_iupac_name: | NORLEUCINE | | Drug_type: | Experimental | | Drugbank_id: | EXPT02355 | | Drug_category: | Phenylalanine-4-Hydroxylase inhibitor | | Organisms_affected: | -1 |
| Species: |
4932 |
| Condition: |
ASF1 |
| Replicates: |
2 |
| Raw OD Value: r im |
0.6239±0.00622254 |
| Normalized OD Score: sc h |
1.0271±0.00661826 |
| Z-Score: |
1.1378±0.274518 |
| p-Value: |
0.264132 |
| Z-Factor: |
-3.52767 |
| Fitness Defect: |
1.3313 |
| Bioactivity Statement: |
Nonactive |
| Experimental Conditions | | | Library: | SPECMTS3 | | Plate Number and Position: | 1|C4 | | Drug Concentration: | 50.00 nM | | OD Absorbance: | 600 nm | | Robot Temperature: | 23.20 Celcius | | Date: | 2008-01-30 YYYY-MM-DD | | Plate CH Control (+): | 0.043425000000000005±0.00182 | | Plate DMSO Control (-): | 0.583225±0.02946 | | Plate Z-Factor: | 0.8463 |
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pdf |
| 6991974 |
(2S)-2-azaniumylhexanoate |
| 6999776 |
(2R)-2-azaniumylhexanoate |
| 9209420 |
(2R)-2-azaniumyl-3-cyclopropyl-propanoate |
| 9209421 |
(2R)-2-amino-3-cyclopropyl-propanoic acid |
| 15605587 |
(2S)-2-amino-2,5,5-trimethyl-hexanoic acid |
| internal high similarity DBLink | Rows returned: 5 | |
| active | Cluster 4858 | Additional Members: 8 | Rows returned: 1 | |
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