| Compound Information | SONAR Target prediction | | Name: | CYCLOLEUCINE | | Unique Identifier: | SPE01502128 | | MolClass: | Checkout models in ver1.5 and ver1.0 | | Molecular Formula: | | | Molecular Weight: | 118.07 g/mol | | X log p: | -2.117 (online calculus) | | Lipinksi Failures | 0 | | TPSA | 17.07 | | Hydrogen Bond Donor Count: | 0 | | Hydrogen Bond Acceptors Count: | 3 | | Rotatable Bond Count: | 1 | | Canonical Smiles: | NC1(CCCC1)C(O)=O | | Source: | synthetic | | Therapeutics: | NMDA receptor antagonist (gly) | | Generic_name: | NORLEUCINE | | Chemical_iupac_name: | NORLEUCINE | | Drug_type: | Experimental | | Drugbank_id: | EXPT02355 | | Drug_category: | Phenylalanine-4-Hydroxylase inhibitor | | Organisms_affected: | -1 |
| Species: |
4932 |
| Condition: |
CKA2 |
| Replicates: |
2 |
| Raw OD Value: r im |
0.8705±0.0053033 |
| Normalized OD Score: sc h |
1.0081±0.000184143 |
| Z-Score: |
0.2909±0.00667464 |
| p-Value: |
0.771162 |
| Z-Factor: |
-5.41765 |
| Fitness Defect: |
0.2599 |
| Bioactivity Statement: |
Nonactive |
| Experimental Conditions | | | Library: | Spectrum | | Plate Number and Position: | 14|E9 | | Drug Concentration: | 50.00 nM | | OD Absorbance: | 600 nm | | Robot Temperature: | 25.50 Celcius | | Date: | 2006-04-03 YYYY-MM-DD | | Plate CH Control (+): | 0.037825±0.00196 | | Plate DMSO Control (-): | 0.83605±0.02015 | | Plate Z-Factor: | 0.9172 |
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ps
pdf |
| 6991974 |
(2S)-2-azaniumylhexanoate |
| 6999776 |
(2R)-2-azaniumylhexanoate |
| 9209420 |
(2R)-2-azaniumyl-3-cyclopropyl-propanoate |
| 9209421 |
(2R)-2-amino-3-cyclopropyl-propanoic acid |
| 15605587 |
(2S)-2-amino-2,5,5-trimethyl-hexanoic acid |
| internal high similarity DBLink | Rows returned: 5 | |
| active | Cluster 4858 | Additional Members: 8 | Rows returned: 1 | |
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