Home | Screening data | Screen comparisons | Search for compounds | Structure search

Compound InformationSONAR Target prediction
Name:

CYCLOLEUCINE

Unique Identifier:SPE01502128
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:
Molecular Weight:118.07 g/mol
X log p:-2.117  (online calculus)
Lipinksi Failures0
TPSA17.07
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:3
Rotatable Bond Count:1
Canonical Smiles:NC1(CCCC1)C(O)=O
Source:synthetic
Therapeutics:NMDA receptor antagonist (gly)
Generic_name:NORLEUCINE
Chemical_iupac_name:NORLEUCINE
Drug_type:Experimental
Drugbank_id:EXPT02355
Drug_category:Phenylalanine-4-Hydroxylase inhibitor
Organisms_affected:-1

Found: 205 nonactive as graph: single | with analogs [1] << Back 1 2 3 4 5 6 7 8 9 10  Next >> [205]
Species: 4932
Condition: BIM1
Replicates: 2
Raw OD Value: r im 0.7075±0.00523259
Normalized OD Score: sc h 1.0105±0.00950068
Z-Score: 0.5572±0.531127
p-Value: 0.603422
Z-Factor: -9.67275
Fitness Defect: 0.5051
Bioactivity Statement: Nonactive
Experimental Conditions
Library:SPECMTS3
Plate Number and Position:1|C4
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:25.60 Celcius
Date:2008-06-24 YYYY-MM-DD
Plate CH Control (+):0.040975±0.00431
Plate DMSO Control (-):0.68025±0.01489
Plate Z-Factor:0.8995
png
ps
pdf

DBLink | Rows returned: 41<< Back 1 2 3 4 5 6 7 Next >> 
5351959 dioxidanium; 1-aminocyclopentane-1-carboxylate; nickel(+2) cation
6394972 copper 1-aminocyclopentane-1-carboxylic acid
6857453 (2S)-2-aminohexanoate
6918961 1-azaniumylcyclopentane-1-carboxylate
6951382 (2S)-2-azaniumyl-3-cyclopropyl-propanoate
6951383 (2S)-2-amino-3-cyclopropyl-propanoic acid

internal high similarity DBLink | Rows returned: 5
JFD 01160 0.9286
LOPAC 00333 0.9286
LOPAC 00681 0.9286
RJC 00670 0.9286
SB 02002 0.9286

active | Cluster 4858 | Additional Members: 8 | Rows returned: 1
SPE01502131 0.2

Service provided by the Mike Tyers Laboratory