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Compound InformationSONAR Target prediction
Name:

ANTIMYCIN A (A1 shown)

Unique Identifier:SPE01502108
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C27H38N2O9
Molecular Weight:496.297 g/mol
X log p:8.094  (online calculus)
Lipinksi Failures3
TPSA113.04
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:11
Rotatable Bond Count:13
Canonical Smiles:CCCCCC1C(OC(=O)CC(C)C)C(C)OC(=O)C(NC(=O)c2cccc(NC=O)c2O)C(C)OC1=O
Source:ex Streptomyces spp
Therapeutics:antifungal, antiviral, interferes in cytochrome oxidation

Found: 55 active | as graph: single | with analogs [1] << Back 1 2 3 4 5 6 7 8 9 10  Next >> [55]
Species: 4932
Condition: SPE00100719
Replicates: 2
Raw OD Value: r im 0.5226±0.00565685
Normalized OD Score: sc h 0.8913±0.00469486
Z-Score: -4.5460±0.229742
p-Value: 0.00000708508
Z-Factor: -0.138539
Fitness Defect: 11.8575
Bioactivity Statement: Active
Experimental Conditions
Library:SpectrumTMP
Plate Number and Position:2|E4
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:20.30 Celcius
Date:2006-12-15 YYYY-MM-DD
Plate CH Control (+):0.039325±0.00179
Plate DMSO Control (-):0.589575±0.02381
Plate Z-Factor:0.8590
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DBLink | Rows returned: 21<< Back 1 2 3 4
7067443 [(2S,3R,6S,7S,8S)-3-[(3-formamido-2-hydroxy-benzoyl)amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7
-yl] 3-methylbutanoate
7067444 [(2S,3R,6S,7R,8R)-3-[(3-formamido-2-hydroxy-benzoyl)amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7
-yl] 3-methylbutanoate
7067445 [(2S,3R,6S,7R,8S)-3-[(3-formamido-2-hydroxy-benzoyl)amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7
-yl] 3-methylbutanoate

internal high similarity DBLink | Rows returned: 0

active | Cluster 5241 | Additional Members: 4 | Rows returned: 0

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