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Compound InformationSONAR Target prediction
Name:

ANTIMYCIN A (A1 shown)

Unique Identifier:SPE01502108
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C27H38N2O9
Molecular Weight:496.297 g/mol
X log p:8.094  (online calculus)
Lipinksi Failures3
TPSA113.04
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:11
Rotatable Bond Count:13
Canonical Smiles:CCCCCC1C(OC(=O)CC(C)C)C(C)OC(=O)C(NC(=O)c2cccc(NC=O)c2O)C(C)OC1=O
Source:ex Streptomyces spp
Therapeutics:antifungal, antiviral, interferes in cytochrome oxidation

Found: 55 active | as graph: single | with analogs 2 3 4 5 6 7 8 9 10  Next >> [55]
Species: 4932
Condition: SPE00240740
Replicates: 2
Raw OD Value: r im 0.6774±0.0157685
Normalized OD Score: sc h 0.9179±0.00570372
Z-Score: -4.0966±0.482192
p-Value: 0.000091015
Z-Factor: -0.107559
Fitness Defect: 9.3045
Bioactivity Statement: Active
Experimental Conditions
Library:SpectrumTMP
Plate Number and Position:2|E4
Drug Concentration:50.00 nM
OD Absorbance:595 nm
Robot Temperature:22.50 Celcius
Date:2006-11-29 YYYY-MM-DD
Plate CH Control (+):0.0383±0.00176
Plate DMSO Control (-):0.757425±0.01725
Plate Z-Factor:0.9143
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DBLink | Rows returned: 21<< Back 1 2 3 4 Next >> 
447892 [(2R,3S,6S,7R,8R)-3-[(3-formamido-2-hydroxy-benzoyl)amino]-2,6-dimethyl-4,9-dioxo-8-pentyl-1,5-dioxonan-
7-yl] 2-methylpropanoate
3084471 [3-[(3-formamido-2-hydroxy-benzoyl)amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl] butanoate
3084472 [8-butyl-3-[(3-formamido-2-hydroxy-benzoyl)amino]-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl] butanoate
4587175 [8-butyl-3-[(3-formamido-2-hydroxy-benzoyl)amino]-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl]
3-methylbutanoate
5287676 [(2S,3S,6R,7R,8R)-3-[(3-formamido-2-hydroxy-benzoyl)amino]-2,6-dimethyl-4,9-dioxo-8-pentyl-1,5-dioxonan-
7-yl] 3-methylbutanoate
5287683 [(2R,3S,6S,7R,8R)-3-[(3-formamido-2-hydroxy-benzoyl)amino]-8-heptyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-
7-yl] (2R)-2-methylbutanoate

internal high similarity DBLink | Rows returned: 0

nonactive | Cluster 5241 | Additional Members: 4 | Rows returned: 2
Prest922 0.0632911392405063
LAT002D02 0

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