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Compound InformationSONAR Target prediction
Name:

ANTIMYCIN A (A1 shown)

Unique Identifier:SPE01502108
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C27H38N2O9
Molecular Weight:496.297 g/mol
X log p:8.094  (online calculus)
Lipinksi Failures3
TPSA113.04
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:11
Rotatable Bond Count:13
Canonical Smiles:CCCCCC1C(OC(=O)CC(C)C)C(C)OC(=O)C(NC(=O)c2cccc(NC=O)c2O)C(C)OC1=O
Source:ex Streptomyces spp
Therapeutics:antifungal, antiviral, interferes in cytochrome oxidation

Found: 55 active | as graph: single | with analogs [1] << Back 1 2 3 4 5 6 7 8 9 10  Next >> [55]
Species: 4932
Condition: SPE00202175
Replicates: 2
Raw OD Value: r im 0.5081±0.031042
Normalized OD Score: sc h 0.8767±0.0429758
Z-Score: -5.2836±2.2531
p-Value: 0.000111921
Z-Factor: -0.854845
Fitness Defect: 9.0977
Bioactivity Statement: Active
Experimental Conditions
Library:SpectrumTMP
Plate Number and Position:2|E4
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:21.50 Celcius
Date:2006-12-19 YYYY-MM-DD
Plate CH Control (+):0.038425±0.00209
Plate DMSO Control (-):0.5774250000000001±0.02001
Plate Z-Factor:0.8634
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DBLink | Rows returned: 212 3 4 Next >> 
2204 [3-[(3-formamido-2-hydroxy-benzoyl)amino]-2,6-dimethyl-4,9-dioxo-8-pentyl-1,5-dioxonan-7-yl]
3-methylbutanoate
10652 [(6S,7S,8R)-8-butyl-3-[(3-formamido-2-hydroxy-benzoyl)amino]-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl]
3-methylbutanoate
12550 [3-[(3-formamido-2-hydroxy-benzoyl)amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl]
3-methylbutanoate
14957 [(2R,3S,6S,7R,8R)-3-[(3-formamido-2-hydroxy-benzoyl)amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7
-yl] 3-methylbutanoate
245869 [(2R,3S,6S,7R,8R)-8-butyl-3-[(3-formamido-2-hydroxy-benzoyl)amino]-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7
-yl] 3-methylbutanoate
447434 [(2R,3S,6S,7R,8R)-3-[(3-formamido-2-hydroxy-benzoyl)amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7
-yl] 2-methylpropanoate

internal high similarity DBLink | Rows returned: 0

active | Cluster 5241 | Additional Members: 4 | Rows returned: 0

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