| Compound Information | SONAR Target prediction | | Name: | PERILLIC ACID (-) | | Unique Identifier: | SPE01502101 | | MolClass: | Checkout models in ver1.5 and ver1.0 | | Molecular Formula: | | | Molecular Weight: | 152.106 g/mol | | X log p: | 1.82 (online calculus) | | Lipinksi Failures | 0 | | TPSA | 17.07 | | Hydrogen Bond Donor Count: | 0 | | Hydrogen Bond Acceptors Count: | 2 | | Rotatable Bond Count: | 2 | | Canonical Smiles: | CC(=C)C1CCC(=CC1)C(O)=O | | Class: | terpene | | Source: | Salvia dorisiana | | Reference: | J Am Chem Soc 72: 2381 (1950); Experientia 26: 473 (1970); J Agric Food Chem 24:
377 (1976) | | Therapeutics: | inhibits posttranslational cys isoprenylation, blocks G-protein |
| Species: |
4932 |
| Condition: |
SKT5 |
| Replicates: |
2 |
| Raw OD Value: r im |
0.6755±0.00289914 |
| Normalized OD Score: sc h |
0.9860±0.00046382 |
| Z-Score: |
-0.6962±0.0271259 |
| p-Value: |
0.486358 |
| Z-Factor: |
-7.53145 |
| Fitness Defect: |
0.7208 |
| Bioactivity Statement: |
Nonactive |
| Experimental Conditions | | | Library: | SPECMTS3 | | Plate Number and Position: | 12|F10 | | Drug Concentration: | 50.00 nM | | OD Absorbance: | 600 nm | | Robot Temperature: | 24.90 Celcius | | Date: | 2008-06-17 YYYY-MM-DD | | Plate CH Control (+): | 0.0407±0.00071 | | Plate DMSO Control (-): | 0.6735±0.01625 | | Plate Z-Factor: | 0.9243 |
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ps
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| 1256 |
4-prop-1-en-2-ylcyclohexene-1-carboxylic acid |
| 296887 |
n/a |
| 562404 |
8-ethenyl-5-methylidene-4,4a,6,7,8,8a-hexahydro-3H-naphthalene-2-carboxylic acid |
| 637233 |
8,11-dimethyl-14-propan-2-yl-bicyclo[9.3.0]tetradeca-4,8,13-triene-4-carboxylic acid |
| 2724160 |
(4S)-4-prop-1-en-2-ylcyclohexene-1-carboxylic acid |
| 5316958 |
(1R,3Z,7Z,11S)-1,4-dimethyl-12-propan-2-yl-bicyclo[9.3.0]tetradeca-3,7,12-triene-8-carboxylic acid |
| internal high similarity DBLink | Rows returned: 1 | |
| active | Cluster 8846 | Additional Members: 5 | Rows returned: 1 | |
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