Compound Information | SONAR Target prediction | Name: | PERILLIC ACID (-) | Unique Identifier: | SPE01502101 | MolClass: | Checkout models in ver1.5 and ver1.0 | Molecular Formula: | | Molecular Weight: | 152.106 g/mol | X log p: | 1.82 (online calculus) | Lipinksi Failures | 0 | TPSA | 17.07 | Hydrogen Bond Donor Count: | 0 | Hydrogen Bond Acceptors Count: | 2 | Rotatable Bond Count: | 2 | Canonical Smiles: | CC(=C)C1CCC(=CC1)C(O)=O | Class: | terpene | Source: | Salvia dorisiana | Reference: | J Am Chem Soc 72: 2381 (1950); Experientia 26: 473 (1970); J Agric Food Chem 24: 377 (1976) | Therapeutics: | inhibits posttranslational cys isoprenylation, blocks G-protein |
Species: |
4932 |
Condition: |
IRE1 |
Replicates: |
2 |
Raw OD Value: r im |
0.6757±0.0388909 |
Normalized OD Score: sc h |
0.7032±0.0257479 |
Z-Score: |
-8.1349±0.449785 |
p-Value: |
0.00000000000000272268 |
Z-Factor: |
0.413898 |
Fitness Defect: |
33.5372 |
Bioactivity Statement: |
Active |
Experimental Conditions | | Library: | Spectrum | Plate Number and Position: | 14|E8 | Drug Concentration: | 50.00 nM | OD Absorbance: | 600 nm | Robot Temperature: | 24.50 Celcius | Date: | 2007-11-23 YYYY-MM-DD | Plate CH Control (+): | 0.03995±0.00055 | Plate DMSO Control (-): | 0.7053750000000001±0.01295 | Plate Z-Factor: | 0.9399 |
| png ps pdf |
1256 |
4-prop-1-en-2-ylcyclohexene-1-carboxylic acid |
296887 |
n/a |
562404 |
8-ethenyl-5-methylidene-4,4a,6,7,8,8a-hexahydro-3H-naphthalene-2-carboxylic acid |
637233 |
8,11-dimethyl-14-propan-2-yl-bicyclo[9.3.0]tetradeca-4,8,13-triene-4-carboxylic acid |
2724160 |
(4S)-4-prop-1-en-2-ylcyclohexene-1-carboxylic acid |
5316958 |
(1R,3Z,7Z,11S)-1,4-dimethyl-12-propan-2-yl-bicyclo[9.3.0]tetradeca-3,7,12-triene-8-carboxylic acid |
internal high similarity DBLink | Rows returned: 1 | |
active | Cluster 8846 | Additional Members: 5 | Rows returned: 1 | |
|