Home | Screening data | Screen comparisons | Search for compounds | Structure search

Compound InformationSONAR Target prediction
Name:

LAPACHOL

Unique Identifier:SPE01501204
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:
Molecular Weight:228.159 g/mol
X log p:10.414  (online calculus)
Lipinksi Failures1
TPSA34.14
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:3
Rotatable Bond Count:2
Canonical Smiles:CC(C)=CCc1c(O)c(=O)c2ccccc2c1=O
Class:quinone
Source:heartwood of Bignoniaceae
Reference:Phytochemistry 14: 1829 (1975)
Therapeutics:antineoplastic, antifungal

Found: 148 active | as graph: single | with analogs [1] << Back 121 122 123 124 125 126 127 128 129 130  Next >> [148]
Species: 4932
Condition: CIN2
Replicates: 2
Raw OD Value: r im 0.7290±0.0104652
Normalized OD Score: sc h 0.9254±0.0000431395
Z-Score: -4.2020±0.0684533
p-Value: 0.0000270374
Z-Factor: 0.32597
Fitness Defect: 10.5183
Bioactivity Statement: Active
Experimental Conditions
Library:Spectrum
Plate Number and Position:23|G8
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:27.30 Celcius
Date:2006-02-14 YYYY-MM-DD
Plate CH Control (+):0.039125±0.00114
Plate DMSO Control (-):0.7667999999999999±0.01242
Plate Z-Factor:0.9268
png
ps
pdf

DBLink | Rows returned: 1
3884 4-hydroxy-3-(3-methylbut-2-enyl)naphthalene-1,2-dione

internal high similarity DBLink | Rows returned: 0

active | Cluster 16242 | Additional Members: 2 | Rows returned: 0
Service provided by the Mike Tyers Laboratory