Home | Screening data | Screen comparisons | Search for compounds | Structure search

Compound InformationSONAR Target prediction
Name:

METHACYCLINE HYDROCHLORIDE

Unique Identifier:SPE01501104
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:
Molecular Weight:455.697 g/mol
X log p:5.229  (online calculus)
Lipinksi Failures1
TPSA54.45
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:10
Rotatable Bond Count:2
Canonical Smiles:Cl.CN(C)C1C2C(O)C3C(=C)c4cccc(O)c4C(=O)C3=C(O)C2(O)C(=O)C(C(N)=O)=C1O
Source:semisynthetic
Therapeutics:antibacterial

Found: 205 nonactive as graph: single | with analogs [1] << Back 91 92 93 94 95 96 97 98 99 100  Next >> [205]
Species: 4932
Condition: BY4741
Replicates: 2
Raw OD Value: r im 0.7650±0.022981
Normalized OD Score: sc h 0.9881±0.0121955
Z-Score: -1.2607±0.416571
p-Value: 0.22694
Z-Factor: -1.8829
Fitness Defect: 1.4831
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Spectrum_ED
Plate Number and Position:6|B6
Drug Concentration:50.00 nM
OD Absorbance:595 nm
Robot Temperature:30.00 Celcius
Date:2010-08-10 YYYY-MM-DD
Plate CH Control (+):0.09149999999999998±0.00600
Plate DMSO Control (-):0.9742499999999997±0.04651
Plate Z-Factor:0.8471
png
ps
pdf

DBLink | Rows returned: 0

internal high similarity DBLink | Rows returned: 2
LOPAC 00868 0.9129
SPE01500266 0.9129

active | Cluster 2358 | Additional Members: 14 | Rows returned: 5
Prest588 0.465909090909091
SPE01501118 0.465909090909091
Prest1251 0.406976744186046
Prest1072 0
SPE01500266 0

Service provided by the Mike Tyers Laboratory