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Compound InformationSONAR Target prediction
Name:

METHACYCLINE HYDROCHLORIDE

Unique Identifier:SPE01501104
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:
Molecular Weight:455.697 g/mol
X log p:5.229  (online calculus)
Lipinksi Failures1
TPSA54.45
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:10
Rotatable Bond Count:2
Canonical Smiles:Cl.CN(C)C1C2C(O)C3C(=C)c4cccc(O)c4C(=O)C3=C(O)C2(O)C(=O)C(C(N)=O)=C1O
Source:semisynthetic
Therapeutics:antibacterial

Found: 205 nonactive as graph: single | with analogs [1] << Back 171 172 173 174 175 176 177 178 179 180  Next >> [205]
Species: 4932
Condition: RNR3
Replicates: 2
Raw OD Value: r im 0.7308±0.0192333
Normalized OD Score: sc h 0.9479±0.015999
Z-Score: -1.5341±0.331427
p-Value: 0.135336
Z-Factor: -1.47099
Fitness Defect: 2
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Spectrum
Plate Number and Position:18|H9
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:24.90 Celcius
Date:2006-04-26 YYYY-MM-DD
Plate CH Control (+):0.039775000000000005±0.00268
Plate DMSO Control (-):0.761375±0.01733
Plate Z-Factor:0.9158
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DBLink | Rows returned: 0

internal high similarity DBLink | Rows returned: 2
LOPAC 00868 0.9129
SPE01500266 0.9129

nonactive | Cluster 2358 | Additional Members: 14 | Rows returned: 111 2 Next >> 
LAT002C08 0.465909090909091
SPE01501118 0.465909090909091
LAT002E08 0.406976744186046
Prest1251 0.406976744186046
Prest630 0.353658536585366
SPE01500457 0.353658536585366

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