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Compound InformationSONAR Target prediction
Name:

METHACYCLINE HYDROCHLORIDE

Unique Identifier:SPE01501104
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:
Molecular Weight:455.697 g/mol
X log p:5.229  (online calculus)
Lipinksi Failures1
TPSA54.45
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:10
Rotatable Bond Count:2
Canonical Smiles:Cl.CN(C)C1C2C(O)C3C(=C)c4cccc(O)c4C(=O)C3=C(O)C2(O)C(=O)C(C(N)=O)=C1O
Source:semisynthetic
Therapeutics:antibacterial

Found: 205 nonactive as graph: single | with analogs 1 2 3 4 5 6 7 8 9 10  Next >> [205]
Species: 4932
Condition: AAT2
Replicates: 2
Raw OD Value: r im 0.7493±0.00601041
Normalized OD Score: sc h 1.0112±0.00851147
Z-Score: 0.5974±0.464878
p-Value: 0.571306
Z-Factor: -6.43076
Fitness Defect: 0.5598
Bioactivity Statement: Nonactive
Experimental Conditions
Library:SPECMTS3
Plate Number and Position:4|B3
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:23.60 Celcius
Date:2008-04-08 YYYY-MM-DD
Plate CH Control (+):0.03925±0.00089
Plate DMSO Control (-):0.7198±0.01536
Plate Z-Factor:0.9260
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DBLink | Rows returned: 0

internal high similarity DBLink | Rows returned: 2
LOPAC 00868 0.9129
SPE01500266 0.9129

active | Cluster 2358 | Additional Members: 14 | Rows returned: 5
Prest588 0.465909090909091
SPE01501118 0.465909090909091
Prest1251 0.406976744186046
Prest1072 0
SPE01500266 0

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