Compound Information | SONAR Target prediction | Name: | FLUNARIZINE HYDROCHLORIDE | Unique Identifier: | SPE01500993 | MolClass: | Checkout models in ver1.5 and ver1.0 | Molecular Formula: | | Molecular Weight: | 449.194 g/mol | X log p: | 32.214 (online calculus) | Lipinksi Failures | 1 | TPSA | 6.48 | Hydrogen Bond Donor Count: | 0 | Hydrogen Bond Acceptors Count: | 2 | Rotatable Bond Count: | 6 | Canonical Smiles: | Cl.Cl.Fc1ccc(cc1)C(N1CCN(CC1)CC=Cc1ccccc1)c1ccc(F)cc1 | Source: | synthetic | Therapeutics: | vasodilator |
Species: |
4932 |
Condition: |
ABP1 |
Replicates: |
2 |
Raw OD Value: r im |
0.2584±0.00961665 |
Normalized OD Score: sc h |
0.3743±0.01757 |
Z-Score: |
-32.0105±2.35022 |
p-Value: |
0 |
Z-Factor: |
0.810768 |
Fitness Defect: |
INF |
Bioactivity Statement: |
Active |
Experimental Conditions | | Library: | SPECMTS3 | Plate Number and Position: | 11|C6 | Drug Concentration: | 50.00 nM | OD Absorbance: | 600 nm | Robot Temperature: | 22.80 Celcius | Date: | 2007-12-20 YYYY-MM-DD | Plate CH Control (+): | 0.0426±0.00145 | Plate DMSO Control (-): | 0.66865±0.01467 | Plate Z-Factor: | 0.9247 |
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5353625 |
1-[bis(4-fluorophenyl)methyl]-4-cinnamyl-2,3,5,6-tetrahydropyrazine |
5388974 |
1-[bis(4-fluorophenyl)methyl]-4-cinnamyl-piperazine; hydrogen(+1) cation; chloride |
6365505 |
1-[bis(4-fluorophenyl)methyl]-4-cinnamyl-piperazine hydrochloride |
internal high similarity DBLink | Rows returned: 2 | |
active | Cluster 3056 | Additional Members: 6 | Rows returned: 2 | |
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