| Compound Information | SONAR Target prediction | | Name: | FLUNARIZINE HYDROCHLORIDE | | Unique Identifier: | SPE01500993 | | MolClass: | Checkout models in ver1.5 and ver1.0 | | Molecular Formula: | | | Molecular Weight: | 449.194 g/mol | | X log p: | 32.214 (online calculus) | | Lipinksi Failures | 1 | | TPSA | 6.48 | | Hydrogen Bond Donor Count: | 0 | | Hydrogen Bond Acceptors Count: | 2 | | Rotatable Bond Count: | 6 | | Canonical Smiles: | Cl.Cl.Fc1ccc(cc1)C(N1CCN(CC1)CC=Cc1ccccc1)c1ccc(F)cc1 | | Source: | synthetic | | Therapeutics: | vasodilator |
| Species: |
4932 |
| Condition: |
BIM1 |
| Replicates: |
2 |
| Raw OD Value: r im |
0.4861±0.00763675 |
| Normalized OD Score: sc h |
0.7154±0.0148021 |
| Z-Score: |
-14.6524±1.95522 |
| p-Value: |
1.73189e-40 |
| Z-Factor: |
0.564877 |
| Fitness Defect: |
91.5542 |
| Bioactivity Statement: |
Active |
| Experimental Conditions | | | Library: | SPECMTS3 | | Plate Number and Position: | 11|C6 | | Drug Concentration: | 50.00 nM | | OD Absorbance: | 600 nm | | Robot Temperature: | 26.20 Celcius | | Date: | 2008-06-24 YYYY-MM-DD | | Plate CH Control (+): | 0.040525±0.00049 | | Plate DMSO Control (-): | 0.660275±0.01711 | | Plate Z-Factor: | 0.9117 |
|  png
ps
pdf |
| 5353625 |
1-[bis(4-fluorophenyl)methyl]-4-cinnamyl-2,3,5,6-tetrahydropyrazine |
| 5388974 |
1-[bis(4-fluorophenyl)methyl]-4-cinnamyl-piperazine; hydrogen(+1) cation; chloride |
| 6365505 |
1-[bis(4-fluorophenyl)methyl]-4-cinnamyl-piperazine hydrochloride |
| internal high similarity DBLink | Rows returned: 2 | |
| active | Cluster 3056 | Additional Members: 6 | Rows returned: 2 | |
|
