Compound Information | SONAR Target prediction | Name: | FLUNARIZINE HYDROCHLORIDE | Unique Identifier: | SPE01500993 | MolClass: | Checkout models in ver1.5 and ver1.0 | Molecular Formula: | | Molecular Weight: | 449.194 g/mol | X log p: | 32.214 (online calculus) | Lipinksi Failures | 1 | TPSA | 6.48 | Hydrogen Bond Donor Count: | 0 | Hydrogen Bond Acceptors Count: | 2 | Rotatable Bond Count: | 6 | Canonical Smiles: | Cl.Cl.Fc1ccc(cc1)C(N1CCN(CC1)CC=Cc1ccccc1)c1ccc(F)cc1 | Source: | synthetic | Therapeutics: | vasodilator |
Species: |
4932 |
Condition: |
BCK1 |
Replicates: |
2 |
Raw OD Value: r im |
0.8675±0.00120208 |
Normalized OD Score: sc h |
0.0776±0.00135784 |
Z-Score: |
-46.8824±1.06215 |
p-Value: |
0 |
Z-Factor: |
0.900098 |
Fitness Defect: |
INF |
Bioactivity Statement: |
Toxic |
Experimental Conditions | | Library: | Spectrum_ED | Plate Number and Position: | 6|A3 | Drug Concentration: | 50.00 nM | OD Absorbance: | 595 nm | Robot Temperature: | 30.00 Celcius | Date: | 2010-08-10 YYYY-MM-DD | Plate CH Control (+): | 0.08725±0.00370 | Plate DMSO Control (-): | 0.9445±0.02697 | Plate Z-Factor: | 0.8822 |
| png ps pdf |
5353625 |
1-[bis(4-fluorophenyl)methyl]-4-cinnamyl-2,3,5,6-tetrahydropyrazine |
5388974 |
1-[bis(4-fluorophenyl)methyl]-4-cinnamyl-piperazine; hydrogen(+1) cation; chloride |
6365505 |
1-[bis(4-fluorophenyl)methyl]-4-cinnamyl-piperazine hydrochloride |
internal high similarity DBLink | Rows returned: 2 | |
active | Cluster 3056 | Additional Members: 6 | Rows returned: 2 | |
|