Home | Screening data | Screen comparisons | Search for compounds | Structure search

Compound InformationSONAR Target prediction
Name:

4`-HYDROXYFLAVANONE

Unique Identifier:SPE01500908
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C15H12O3
Molecular Weight:228.159 g/mol
X log p:16.734  (online calculus)
Lipinksi Failures1
TPSA26.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:3
Rotatable Bond Count:1
Canonical Smiles:Oc1ccc(cc1)C1CC(=O)c2ccccc2O1
Source:semisynthetic analog
Generic_name:4--HYDROXYFLAVANONE
Chemical_iupac_name:2-(4-HYDROXY-PHENYL)-CHROMAN-4-ONE
Drug_type:Experimental
Drugbank_id:EXPT01169
Logp:2.56
Drug_category:Chalcone--Flavonone Isomerase 1 inhibitor
Organisms_affected:-1

Found: 78 active | as graph: single | with analogs [1] << Back 31 32 33 34 35 36 37 38 39 40  Next >> [78]
Species: 4932
Condition: HXT1
Replicates: 2
Raw OD Value: r im 0.6353±0.000848528
Normalized OD Score: sc h 0.9167±0.000896656
Z-Score: -4.3922±0.132821
p-Value: 0.0000122347
Z-Factor: -17.1443
Fitness Defect: 11.3112
Bioactivity Statement: Active
Experimental Conditions
Library:Spectrum
Plate Number and Position:24|D3
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:24.70 Celcius
Date:2007-11-27 YYYY-MM-DD
Plate CH Control (+):0.040900000000000006±0.00098
Plate DMSO Control (-):0.68455±0.14442
Plate Z-Factor:0.1679
png
ps
pdf

DBLink | Rows returned: 3
165506 2-(4-hydroxyphenyl)chroman-4-one
688859 (2S)-2-(4-hydroxyphenyl)chroman-4-one
688860 (2R)-2-(4-hydroxyphenyl)chroman-4-one

internal high similarity DBLink | Rows returned: 13<< Back 1 2 3
JFD 00170 0.9829

active | Cluster 10088 | Additional Members: 12 | Rows returned: 0
Service provided by the Mike Tyers Laboratory