Home | Screening data | Screen comparisons | Search for compounds | Structure search

Compound InformationSONAR Target prediction
Name:

4`-HYDROXYFLAVANONE

Unique Identifier:SPE01500908
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C15H12O3
Molecular Weight:228.159 g/mol
X log p:16.734  (online calculus)
Lipinksi Failures1
TPSA26.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:3
Rotatable Bond Count:1
Canonical Smiles:Oc1ccc(cc1)C1CC(=O)c2ccccc2O1
Source:semisynthetic analog
Generic_name:4--HYDROXYFLAVANONE
Chemical_iupac_name:2-(4-HYDROXY-PHENYL)-CHROMAN-4-ONE
Drug_type:Experimental
Drugbank_id:EXPT01169
Logp:2.56
Drug_category:Chalcone--Flavonone Isomerase 1 inhibitor
Organisms_affected:-1

Found: 78 active | as graph: single | with analogs [1] << Back 21 22 23 24 25 26 27 28 29 30  Next >> [78]
Species: 4932
Condition: GCN5
Replicates: 2
Raw OD Value: r im 0.2151±0.0304056
Normalized OD Score: sc h 0.7180±0.00755081
Z-Score: -4.8352±0.162542
p-Value: 0.00000154871
Z-Factor: -1.53575
Fitness Defect: 13.3781
Bioactivity Statement: Active
Experimental Conditions
Library:Spectrum
Plate Number and Position:24|D3
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:26.30 Celcius
Date:2007-10-30 YYYY-MM-DD
Plate CH Control (+):0.041075±0.00060
Plate DMSO Control (-):0.300275±0.05747
Plate Z-Factor:0.2139
png
ps
pdf

DBLink | Rows returned: 3
165506 2-(4-hydroxyphenyl)chroman-4-one
688859 (2S)-2-(4-hydroxyphenyl)chroman-4-one
688860 (2R)-2-(4-hydroxyphenyl)chroman-4-one

internal high similarity DBLink | Rows returned: 13<< Back 1 2 3
JFD 00170 0.9829

active | Cluster 10088 | Additional Members: 12 | Rows returned: 0
Service provided by the Mike Tyers Laboratory