Home | Screening data | Screen comparisons | Search for compounds | Structure search

Compound InformationSONAR Target prediction
Name:

4`-HYDROXYFLAVANONE

Unique Identifier:SPE01500908
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C15H12O3
Molecular Weight:228.159 g/mol
X log p:16.734  (online calculus)
Lipinksi Failures1
TPSA26.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:3
Rotatable Bond Count:1
Canonical Smiles:Oc1ccc(cc1)C1CC(=O)c2ccccc2O1
Source:semisynthetic analog
Generic_name:4--HYDROXYFLAVANONE
Chemical_iupac_name:2-(4-HYDROXY-PHENYL)-CHROMAN-4-ONE
Drug_type:Experimental
Drugbank_id:EXPT01169
Logp:2.56
Drug_category:Chalcone--Flavonone Isomerase 1 inhibitor
Organisms_affected:-1

Found: 78 active | as graph: single | with analogs [1] << Back 11 12 13 14 15 16 17 18 19 20  Next >> [78]
Species: 4932
Condition: CHS5
Replicates: 2
Raw OD Value: r im 0.6130±0.0548715
Normalized OD Score: sc h 0.8201±0.0719349
Z-Score: -8.7737±3.72351
p-Value: 0.000000000410642
Z-Factor: -0.452758
Fitness Defect: 21.6133
Bioactivity Statement: Active
Experimental Conditions
Library:Spectrum
Plate Number and Position:24|D3
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:26.90 Celcius
Date:2006-03-28 YYYY-MM-DD
Plate CH Control (+):0.03985±0.00170
Plate DMSO Control (-):0.734275±0.01140
Plate Z-Factor:0.9363
png
ps
pdf

DBLink | Rows returned: 3
165506 2-(4-hydroxyphenyl)chroman-4-one
688859 (2S)-2-(4-hydroxyphenyl)chroman-4-one
688860 (2R)-2-(4-hydroxyphenyl)chroman-4-one

internal high similarity DBLink | Rows returned: 13<< Back 1 2 3 Next >> 
SPE01600561 0.9350
BTB 13718 0.9407
JFD 00172 0.9417
SPE01500746 0.9426
SPE00200343 0.9652
BTB 13717 0.9652

active | Cluster 10088 | Additional Members: 12 | Rows returned: 0
Service provided by the Mike Tyers Laboratory