Compound Information | SONAR Target prediction | Name: | CHOLEST-5-EN-3-ONE | Unique Identifier: | SPE01500849 | MolClass: | Checkout models in ver1.5 and ver1.0 | Molecular Formula: | | Molecular Weight: | 340.288 g/mol | X log p: | 3.186 (online calculus) | Lipinksi Failures | 0 | TPSA | 17.07 | Hydrogen Bond Donor Count: | 0 | Hydrogen Bond Acceptors Count: | 1 | Rotatable Bond Count: | 5 | Canonical Smiles: | CC(C)CCCC(C)C1CCC2C3CC=C4CC(=O)CCC4(C)C3CCC12C | Class: | sterol | Source: | animal fats; mp 79-80 C | Reference: | J Am Chem Soc 75: 3500 (1953) |
Species: |
4932 |
Condition: |
CDC73 |
Replicates: |
2 |
Raw OD Value: r im |
0.3154±0.0274357 |
Normalized OD Score: sc h |
0.7526±0.0410733 |
Z-Score: |
-6.2137±0.708427 |
p-Value: |
0.00000000556804 |
Z-Factor: |
-2.95672 |
Fitness Defect: |
19.0062 |
Bioactivity Statement: |
Active |
Experimental Conditions | | Library: | Spectrum | Plate Number and Position: | 8|A8 | Drug Concentration: | 50.00 nM | OD Absorbance: | 600 nm | Robot Temperature: | 26.70 Celcius | Date: | 2007-09-19 YYYY-MM-DD | Plate CH Control (+): | 0.040249999999999994±0.00037 | Plate DMSO Control (-): | 0.40585±0.07978 | Plate Z-Factor: | 0.2653 |
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373581 |
8,8-dimethylbicyclo[3.2.1]oct-6-en-4-one |
439372 |
10,13-dimethyl-1,2,4,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one |
535380 |
1,1,4a-trimethyl-4,5,6,7-tetrahydro-3H-naphthalen-2-one |
548749 |
3,3a,4,6a-tetrahydro-2H-pentalen-1-one |
556081 |
n/a |
556751 |
5-methyl-3,3a,4,6a-tetrahydro-2H-pentalen-1-one |
internal high similarity DBLink | Rows returned: 1 | |
active | Cluster 17506 | Additional Members: 20 | Rows returned: 3 | |
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