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Compound InformationSONAR Target prediction
Name:

NARINGENIN

Unique Identifier:SPE01500746
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:
Molecular Weight:260.158 g/mol
X log p:12.698  (online calculus)
Lipinksi Failures1
TPSA26.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:5
Rotatable Bond Count:1
Canonical Smiles:Oc1ccc(cc1)C1CC(=O)c2c(O)cc(O)cc2O1
Class:flavan
Source:widely distributed in plants
Therapeutics:antiulcer, gibberellin antagonist
Generic_name:NARINGENIN
Chemical_iupac_name:NARINGENIN
Drug_type:Experimental
Kegg_compound_id:C00509
Drugbank_id:EXPT02295
Logp:2.211
Cas_registry_number:480-41-1
Drug_category:Chalcone-Flavonone Isomerase 1 inhibitor
Organisms_affected:-1

Found: 205 nonactive as graph: single | with analogs [1] << Back 31 32 33 34 35 36 37 38 39 40  Next >> [205]
Species: 4932
Condition: CTF18
Replicates: 2
Raw OD Value: r im 0.6031±0.00339411
Normalized OD Score: sc h 1.0222±0.00427664
Z-Score: 0.9920±0.0751257
p-Value: 0.321902
Z-Factor: -7.85221
Fitness Defect: 1.1335
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Spectrum
Plate Number and Position:19|D3
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:26.20 Celcius
Date:2007-11-01 YYYY-MM-DD
Plate CH Control (+):0.042499999999999996±0.00087
Plate DMSO Control (-):0.580875±0.10525
Plate Z-Factor:0.3799
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DBLink | Rows returned: 3
932 5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one
439246 (2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one
667495 (2R)-5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one

internal high similarity DBLink | Rows returned: 131 2 3 Next >> 
BTB 13717 0.9098
SPE00200343 0.9098
JFD 00170 0.9274
RJC 01638 0.9280
SPE00310012 0.9313
BTB 12807 0.9313

active | Cluster 14672 | Additional Members: 12 | Rows returned: 1
SPE01504154 0.416666666666667

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