| Compound Information | SONAR Target prediction | | Name: | NARINGENIN | | Unique Identifier: | SPE01500746 | | MolClass: | Checkout models in ver1.5 and ver1.0 | | Molecular Formula: | | | Molecular Weight: | 260.158 g/mol | | X log p: | 12.698 (online calculus) | | Lipinksi Failures | 1 | | TPSA | 26.3 | | Hydrogen Bond Donor Count: | 0 | | Hydrogen Bond Acceptors Count: | 5 | | Rotatable Bond Count: | 1 | | Canonical Smiles: | Oc1ccc(cc1)C1CC(=O)c2c(O)cc(O)cc2O1 | | Class: | flavan | | Source: | widely distributed in plants | | Therapeutics: | antiulcer, gibberellin antagonist | | Generic_name: | NARINGENIN | | Chemical_iupac_name: | NARINGENIN | | Drug_type: | Experimental | | Kegg_compound_id: | C00509 | | Drugbank_id: | EXPT02295 | | Logp: | 2.211 | | Cas_registry_number: | 480-41-1 | | Drug_category: | Chalcone-Flavonone Isomerase 1 inhibitor | | Organisms_affected: | -1 |
| Species: |
4932 |
| Condition: |
WHI5 |
| Replicates: |
2 |
| Raw OD Value: r im |
0.6935±0.00685894 |
| Normalized OD Score: sc h |
0.9961±0.0141505 |
| Z-Score: |
0.0143±0.483756 |
| p-Value: |
0.732326 |
| Z-Factor: |
-60.9775 |
| Fitness Defect: |
0.3115 |
| Bioactivity Statement: |
Nonactive |
| Experimental Conditions | | | Library: | SPECMTS3 | | Plate Number and Position: | 21|H9 | | Drug Concentration: | 50.00 nM | | OD Absorbance: | 600 nm | | Robot Temperature: | 26.10 Celcius | | Date: | 2008-09-16 YYYY-MM-DD | | Plate CH Control (+): | 0.041874999999999996±0.00098 | | Plate DMSO Control (-): | 0.685125±0.01193 | | Plate Z-Factor: | 0.9521 |
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| DBLink | Rows returned: 3 | |
| 932 |
5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one |
| 439246 |
(2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one |
| 667495 |
(2R)-5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one |
| internal high similarity DBLink | Rows returned: 13 | << Back 1 2 3 |
| active | Cluster 14672 | Additional Members: 12 | Rows returned: 1 | |
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