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Compound InformationSONAR Target prediction
Name:

NARINGENIN

Unique Identifier:SPE01500746
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:
Molecular Weight:260.158 g/mol
X log p:12.698  (online calculus)
Lipinksi Failures1
TPSA26.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:5
Rotatable Bond Count:1
Canonical Smiles:Oc1ccc(cc1)C1CC(=O)c2c(O)cc(O)cc2O1
Class:flavan
Source:widely distributed in plants
Therapeutics:antiulcer, gibberellin antagonist
Generic_name:NARINGENIN
Chemical_iupac_name:NARINGENIN
Drug_type:Experimental
Kegg_compound_id:C00509
Drugbank_id:EXPT02295
Logp:2.211
Cas_registry_number:480-41-1
Drug_category:Chalcone-Flavonone Isomerase 1 inhibitor
Organisms_affected:-1

Found: 205 nonactive as graph: single | with analogs [1] << Back 1 2 3 4 5 6 7 8 9 10  Next >> [205]
Species: 4932
Condition: CLN2
Replicates: 2
Raw OD Value: r im 0.6405±0.00212132
Normalized OD Score: sc h 0.9677±0.00460921
Z-Score: 0.6213±0.174843
p-Value: 0.53749
Z-Factor: -10.2394
Fitness Defect: 0.6208
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Spectrum_ED
Plate Number and Position:18|C5
Drug Concentration:50.00 nM
OD Absorbance:595 nm
Robot Temperature:30.00 Celcius
Date:2010-08-10 YYYY-MM-DD
Plate CH Control (+):0.09875±0.00560
Plate DMSO Control (-):0.8907499999999999±0.02627
Plate Z-Factor:0.8855
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DBLink | Rows returned: 3
932 5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one
439246 (2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one
667495 (2R)-5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one

internal high similarity DBLink | Rows returned: 13<< Back 1 2 3 Next >> 
SPE01500908 0.9426
NRB 00919 0.9440
SPE01500733 0.9449
SPE01600561 0.9600
JFD 01216 0.9606
JFD 00172 0.9672

active | Cluster 14672 | Additional Members: 12 | Rows returned: 1
SPE01504154 0.416666666666667

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