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Compound InformationSONAR Target prediction
Name:

QUERCETIN

Unique Identifier:SPE01500672
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:
Molecular Weight:292.156 g/mol
X log p:11.519  (online calculus)
Lipinksi Failures1
TPSA26.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:7
Rotatable Bond Count:1
Canonical Smiles:Oc1cc(O)c2C(=O)C(O)=C(Oc2c1)c1ccc(O)c(O)c1
Class:flavone
Source:Solanaceae, Rhamnaceae, Passifloraceae, Umbelliferae genera
Reference:Chem Ber 103:3674 (1970); Experientia 28:380 (1972); Phytochemistry 12:1787 (1973);
IARC Monog 31:213 Suppl 7:71 (1983); Antiviral Res 12:99 (1989)
Therapeutics:capillary protectant, antioxidant. antineoplastic, anti-HIV; LD50(mouse) 159 mg/kg
po
Generic_name:2-(3,4,5-TRIHYDROXYPHENYL)-3,5,7-TRIHYDR
Chemical_iupac_name:3,5,7-TRIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-4H-CHROMEN-4-ONE
Drug_type:Experimental
Drugbank_id:EXPT02265
Drug_category:Phosphatidylinositol 3-Kinase Catalytic Subu inhibitor
Organisms_affected:-1

Found: 88 active | as graph: single | with analogs [1] << Back 81 82 83 84 85 86 87 88 Next >> [88]
Species: 4932
Condition: MAD1
Replicates: 2
Raw OD Value: r im 0.6542±0.0475883
Normalized OD Score: sc h 0.9153±0.00909102
Z-Score: -4.8361±0.269468
p-Value: 0.00000194549
Z-Factor: -14.8637
Fitness Defect: 13.15
Bioactivity Statement: Active
Experimental Conditions
Library:Spectrum
Plate Number and Position:19|C6
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:26.80 Celcius
Date:2007-10-05 YYYY-MM-DD
Plate CH Control (+):0.0406±0.00072
Plate DMSO Control (-):0.69875±0.13029
Plate Z-Factor:0.3733
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DBLink | Rows returned: 3
5280343 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromen-4-one
5281672 3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)chromen-4-one
5284452 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromen-4-one dihydrate

internal high similarity DBLink | Rows returned: 122 Next >> 
LOPAC 01047 0.9012
SPE01502259 0.9012
SPE01504130 0.9146
NRB 00325 0.9162
SPE01500732 0.9419
SPE00300538 0.9425

nonactive | Cluster 10732 | Additional Members: 22 | Rows returned: 82 Next >> 
SPE01505143 0.464285714285714
LOPAC 01047 0.421052631578947
SPE01502259 0.421052631578947
SPE01504065 0.326923076923077
LOPAC 01061 0.326923076923077
LAT007F04 0

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