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Compound InformationSONAR Target prediction
Name:

TRYPTOPHAN

Unique Identifier:SPE01500600
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:
Molecular Weight:192.13 g/mol
X log p:8.98  (online calculus)
Lipinksi Failures1
TPSA17.07
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:4
Rotatable Bond Count:3
Canonical Smiles:NC(Cc1cnc2ccccc12)C(O)=O
Class:amino acid
Source:many plants, animal protein
Reference:Biochem J 29:2256 (1935); JACS 67:36 (1945); Aust J Chem 16:246 (1963)
Therapeutics:antidepressant, nutrient; LD50(rat) 1634 mg/kg ip

Found: 205 nonactive as graph: single | with analogs [1] << Back 61 62 63 64 65 66 67 68 69 70  Next >> [205]
Species: 4932
Condition: NAT1
Replicates: 2
Raw OD Value: r im 0.7260±0.000141421
Normalized OD Score: sc h 1.0260±0.00492441
Z-Score: 1.5609±0.341148
p-Value: 0.129224
Z-Factor: -1.41631
Fitness Defect: 2.0462
Bioactivity Statement: Nonactive
Experimental Conditions
Library:SPECMTS3
Plate Number and Position:19|D5
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:26.70 Celcius
Date:2008-06-26 YYYY-MM-DD
Plate CH Control (+):0.040275±0.00070
Plate DMSO Control (-):0.69565±0.01295
Plate Z-Factor:0.9248
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DBLink | Rows returned: 0

internal high similarity DBLink | Rows returned: 5
RH 01792 0.9101
RJC 01802 0.9101
LOPAC 00558 1.0000
RH 01445 1.0000
SB 01750 1.0000

active | Cluster 7695 | Additional Members: 15 | Rows returned: 0
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