Home | Screening data | Screen comparisons | Search for compounds | Structure search

Compound InformationSONAR Target prediction
Name:

TRYPTOPHAN

Unique Identifier:SPE01500600
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:
Molecular Weight:192.13 g/mol
X log p:8.98  (online calculus)
Lipinksi Failures1
TPSA17.07
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:4
Rotatable Bond Count:3
Canonical Smiles:NC(Cc1cnc2ccccc12)C(O)=O
Class:amino acid
Source:many plants, animal protein
Reference:Biochem J 29:2256 (1935); JACS 67:36 (1945); Aust J Chem 16:246 (1963)
Therapeutics:antidepressant, nutrient; LD50(rat) 1634 mg/kg ip

Found: 205 nonactive as graph: single | with analogs [1] << Back 11 12 13 14 15 16 17 18 19 20  Next >> [205]
Species: 4932
Condition: TOR1
Replicates: 2
Raw OD Value: r im 0.9609±0.00777817
Normalized OD Score: sc h 0.9780±0.0120401
Z-Score: 0.6581±0.337822
p-Value: 0.522362
Z-Factor: -4.1998
Fitness Defect: 0.6494
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Spectrum_ED
Plate Number and Position:2|D3
Drug Concentration:50.00 nM
OD Absorbance:595 nm
Robot Temperature:30.00 Celcius
Date:2012-09-18 YYYY-MM-DD
Plate CH Control (+):0.0005499999999999999±0.00192
Plate DMSO Control (-):1.004±0.01932
Plate Z-Factor:0.9291
png
ps
pdf

DBLink | Rows returned: 0

internal high similarity DBLink | Rows returned: 5
RH 01792 0.9101
RJC 01802 0.9101
LOPAC 00558 1.0000
RH 01445 1.0000
SB 01750 1.0000

active | Cluster 7695 | Additional Members: 15 | Rows returned: 0
Service provided by the Mike Tyers Laboratory