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Compound InformationSONAR Target prediction
Name:

TRYPTOPHAN

Unique Identifier:SPE01500600
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:
Molecular Weight:192.13 g/mol
X log p:8.98  (online calculus)
Lipinksi Failures1
TPSA17.07
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:4
Rotatable Bond Count:3
Canonical Smiles:NC(Cc1cnc2ccccc12)C(O)=O
Class:amino acid
Source:many plants, animal protein
Reference:Biochem J 29:2256 (1935); JACS 67:36 (1945); Aust J Chem 16:246 (1963)
Therapeutics:antidepressant, nutrient; LD50(rat) 1634 mg/kg ip

Found: 205 nonactive as graph: single | with analogs [1] << Back 111 112 113 114 115 116 117 118 119 120  Next >> [205]
Species: 4932
Condition: BIK1
Replicates: 2
Raw OD Value: r im 0.6543±0.0164756
Normalized OD Score: sc h 0.9803±0.00686196
Z-Score: -0.8641±0.307592
p-Value: 0.398678
Z-Factor: -3.91454
Fitness Defect: 0.9196
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Spectrum
Plate Number and Position:20|A6
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:24.40 Celcius
Date:2007-11-08 YYYY-MM-DD
Plate CH Control (+):0.040525000000000005±0.00202
Plate DMSO Control (-):0.66095±0.01508
Plate Z-Factor:0.9163
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DBLink | Rows returned: 0

internal high similarity DBLink | Rows returned: 5
RH 01792 0.9101
RJC 01802 0.9101
LOPAC 00558 1.0000
RH 01445 1.0000
SB 01750 1.0000

active | Cluster 7695 | Additional Members: 15 | Rows returned: 0
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