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Compound InformationSONAR Target prediction
Name:

TRIMEPRAZINE TARTRATE

Unique Identifier:SPE01500593
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:
Molecular Weight:420.311 g/mol
X log p:17.975  (online calculus)
Lipinksi Failures1
TPSA31.78
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:2
Rotatable Bond Count:4
Canonical Smiles:CC(CN(C)C)CN1c2ccccc2Sc2ccccc12.OC(C(O)C(O)=O)C(O)=O
Source:synthetic
Therapeutics:antipruritic

Found: 605 nonactive | as graph: single | with analogs [1] << Back 61 62 63 64 65 66 67 68 69 70  Next >> [605]
Species: 4932
Condition: SPE00100101
Replicates: 2
Raw OD Value: r im 0.5003±0.00247487
Normalized OD Score: sc h 1.0450±0.00883624
Z-Score: 0.9520±0.164608
p-Value: 0.344348
Z-Factor: -7.51065
Fitness Defect: 1.0661
Bioactivity Statement: Nonactive
Experimental Conditions
Library:SpectrumTMP
Plate Number and Position:2|A8
Drug Concentration:50.00 nM
OD Absorbance:595 nm
Robot Temperature:21.50 Celcius
Date:2006-12-14 YYYY-MM-DD
Plate CH Control (+):0.038675±0.00169
Plate DMSO Control (-):0.50495±0.02621
Plate Z-Factor:0.7785
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DBLink | Rows returned: 5
441236 (2R,3R)-2,3-dihydroxybutanedioic acid; N,N,2-trimethyl-3-phenothiazin-10-yl-propan-1-amine
5702128 2,3-dihydroxybutanedioic acid; N,N,2-trimethyl-3-phenothiazin-10-yl-propan-1-amine
6419902 2,3-dihydroxybutanedioic acid; N,N,2-trimethyl-3-phenothiazin-10-yl-propan-1-amine
6451200 (2R,3R)-2,3-dihydroxybutanedioic acid; N,N,2-trimethyl-3-phenothiazin-10-yl-propan-1-amine
6604495 (2R,3S)-2,3-dihydroxybutanedioic acid; (2S)-N,N,2-trimethyl-3-phenothiazin-10-yl-propan-1-amine

internal high similarity DBLink | Rows returned: 0

active | Cluster 15250 | Additional Members: 5 | Rows returned: 1
Prest1008 0.272727272727273

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