Home | Screening data | Screen comparisons | Search for compounds | Structure search

Compound InformationSONAR Target prediction
Name:

TOLNAFTATE

Unique Identifier:SPE01500583
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:
Molecular Weight:290.275 g/mol
X log p:24.089  (online calculus)
Lipinksi Failures1
TPSA44.56
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:2
Rotatable Bond Count:4
Canonical Smiles:CN(C(=S)Oc1ccc2ccccc2c1)c1cccc(C)c1
Source:synthetic; SCH-10144
Therapeutics:antifungal

Found: 17 active | as graph: single | with analogs << Back 1 2 3 4 5 6 7 8 9 10  Next >> 
Species: 4932
Condition: SPE00300348
Replicates: 2
Raw OD Value: r im 0.0703±0.00381838
Normalized OD Score: sc h 1.2850±0.0396339
Z-Score: 4.0978±0.468833
p-Value: 0.0000875892
Z-Factor: -3.20252
Fitness Defect: 9.3429
Bioactivity Statement: Active
Experimental Conditions
Library:SpectrumTMP
Plate Number and Position:2|A7
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:22.30 Celcius
Date:2006-12-21 YYYY-MM-DD
Plate CH Control (+):0.0403±0.00073
Plate DMSO Control (-):0.057±0.25343
Plate Z-Factor:-2.5571
png
ps
pdf

DBLink | Rows returned: 1
5510 N-methyl-N-(3-methylphenyl)-1-naphthalen-2-yloxy-methanethioamide

internal high similarity DBLink | Rows returned: 1
BTB 13928 1.0000

active | Cluster 1478 | Additional Members: 4 | Rows returned: 0
Service provided by the Mike Tyers Laboratory