Home | Screening data | Screen comparisons | Search for compounds | Structure search

Compound InformationSONAR Target prediction
Name:

TOLNAFTATE

Unique Identifier:SPE01500583
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:
Molecular Weight:290.275 g/mol
X log p:24.089  (online calculus)
Lipinksi Failures1
TPSA44.56
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:2
Rotatable Bond Count:4
Canonical Smiles:CN(C(=S)Oc1ccc2ccccc2c1)c1cccc(C)c1
Source:synthetic; SCH-10144
Therapeutics:antifungal

Found: 601 nonactive | as graph: single | with analogs [1] << Back 541 542 543 544 545 546 547 548 549 550  Next >> [601]
Species: 4932
Condition: KAR3
Replicates: 2
Raw OD Value: r im 0.6255±0.00148492
Normalized OD Score: sc h 0.9725±0.00244598
Z-Score: -1.2850±0.149668
p-Value: 0.201312
Z-Factor: -155.111
Fitness Defect: 1.6029
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Spectrum
Plate Number and Position:16|A11
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:27.50 Celcius
Date:2007-09-06 YYYY-MM-DD
Plate CH Control (+):0.042825±0.00152
Plate DMSO Control (-):0.6207499999999999±0.11110
Plate Z-Factor:0.3927
png
ps
pdf

DBLink | Rows returned: 1
5510 N-methyl-N-(3-methylphenyl)-1-naphthalen-2-yloxy-methanethioamide

internal high similarity DBLink | Rows returned: 1
BTB 13928 1.0000

active | Cluster 1478 | Additional Members: 4 | Rows returned: 0
Service provided by the Mike Tyers Laboratory