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Compound InformationSONAR Target prediction
Name:

TOLNAFTATE

Unique Identifier:SPE01500583
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:
Molecular Weight:290.275 g/mol
X log p:24.089  (online calculus)
Lipinksi Failures1
TPSA44.56
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:2
Rotatable Bond Count:4
Canonical Smiles:CN(C(=S)Oc1ccc2ccccc2c1)c1cccc(C)c1
Source:synthetic; SCH-10144
Therapeutics:antifungal

Found: 601 nonactive | as graph: single | with analogs [1] << Back 521 522 523 524 525 526 527 528 529 530  Next >> [601]
Species: 4932
Condition: COT1
Replicates: 2
Raw OD Value: r im 0.6738±0.0120208
Normalized OD Score: sc h 0.9753±0.00608141
Z-Score: -1.2803±0.298924
p-Value: 0.210456
Z-Factor: -18.115
Fitness Defect: 1.5585
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Spectrum
Plate Number and Position:16|A11
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:25.70 Celcius
Date:2007-11-20 YYYY-MM-DD
Plate CH Control (+):0.0401±0.00097
Plate DMSO Control (-):0.6786999999999999±0.16177
Plate Z-Factor:0.1754
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DBLink | Rows returned: 1
5510 N-methyl-N-(3-methylphenyl)-1-naphthalen-2-yloxy-methanethioamide

internal high similarity DBLink | Rows returned: 1
BTB 13928 1.0000

active | Cluster 1478 | Additional Members: 4 | Rows returned: 0
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