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Compound InformationSONAR Target prediction
Name:

TOLNAFTATE

Unique Identifier:SPE01500583
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:
Molecular Weight:290.275 g/mol
X log p:24.089  (online calculus)
Lipinksi Failures1
TPSA44.56
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:2
Rotatable Bond Count:4
Canonical Smiles:CN(C(=S)Oc1ccc2ccccc2c1)c1cccc(C)c1
Source:synthetic; SCH-10144
Therapeutics:antifungal

Found: 601 nonactive | as graph: single | with analogs [1] << Back 441 442 443 444 445 446 447 448 449 450  Next >> [601]
Species: 4932
Condition: SRS2
Replicates: 2
Raw OD Value: r im 0.6744±0.0181019
Normalized OD Score: sc h 0.9901±0.0238566
Z-Score: -0.4937±1.16068
p-Value: 0.466186
Z-Factor: -26.2182
Fitness Defect: 0.7632
Bioactivity Statement: Nonactive
Experimental Conditions
Library:SPECMTS3
Plate Number and Position:7|E2
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:21.10 Celcius
Date:2008-01-22 YYYY-MM-DD
Plate CH Control (+):0.0422±0.00092
Plate DMSO Control (-):0.6673±0.02768
Plate Z-Factor:0.9328
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DBLink | Rows returned: 1
5510 N-methyl-N-(3-methylphenyl)-1-naphthalen-2-yloxy-methanethioamide

internal high similarity DBLink | Rows returned: 1
BTB 13928 1.0000

active | Cluster 1478 | Additional Members: 4 | Rows returned: 0
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