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Compound InformationSONAR Target prediction
Name:

TOLNAFTATE

Unique Identifier:SPE01500583
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:
Molecular Weight:290.275 g/mol
X log p:24.089  (online calculus)
Lipinksi Failures1
TPSA44.56
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:2
Rotatable Bond Count:4
Canonical Smiles:CN(C(=S)Oc1ccc2ccccc2c1)c1cccc(C)c1
Source:synthetic; SCH-10144
Therapeutics:antifungal

Found: 601 nonactive | as graph: single | with analogs [1] << Back 381 382 383 384 385 386 387 388 389 390  Next >> [601]
Species: 4932
Condition: SPE01503602
Replicates: 2
Raw OD Value: r im 0.4131±0.00558614
Normalized OD Score: sc h 0.9752±0.0333803
Z-Score: -0.1609±0.216359
p-Value: 0.87368
Z-Factor: -3.0999
Fitness Defect: 0.135
Bioactivity Statement: Nonactive
Experimental Conditions
Library:SpectrumTMP
Plate Number and Position:2|A7
Drug Concentration:50.00 nM
OD Absorbance:595 nm
Robot Temperature:22.40 Celcius
Date:2006-11-15 YYYY-MM-DD
Plate CH Control (+):0.0402±0.00163
Plate DMSO Control (-):0.41490000000000005±0.22464
Plate Z-Factor:-0.1707
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DBLink | Rows returned: 1
5510 N-methyl-N-(3-methylphenyl)-1-naphthalen-2-yloxy-methanethioamide

internal high similarity DBLink | Rows returned: 1
BTB 13928 1.0000

active | Cluster 1478 | Additional Members: 4 | Rows returned: 0
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