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Compound InformationSONAR Target prediction
Name:

TOLNAFTATE

Unique Identifier:SPE01500583
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:
Molecular Weight:290.275 g/mol
X log p:24.089  (online calculus)
Lipinksi Failures1
TPSA44.56
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:2
Rotatable Bond Count:4
Canonical Smiles:CN(C(=S)Oc1ccc2ccccc2c1)c1cccc(C)c1
Source:synthetic; SCH-10144
Therapeutics:antifungal

Found: 601 nonactive | as graph: single | with analogs [1] << Back 301 302 303 304 305 306 307 308 309 310  Next >> [601]
Species: 4932
Condition: SPE00100009
Replicates: 2
Raw OD Value: r im 0.3840±0.016617
Normalized OD Score: sc h 1.2636±0.000797028
Z-Score: 3.3519±0.774779
p-Value: 0.00257152
Z-Factor: -24.5035
Fitness Defect: 5.9633
Bioactivity Statement: Nonactive
Experimental Conditions
Library:SpectrumTMP
Plate Number and Position:2|A7
Drug Concentration:50.00 nM
OD Absorbance:595 nm
Robot Temperature:22.40 Celcius
Date:2006-11-15 YYYY-MM-DD
Plate CH Control (+):0.040525±0.00215
Plate DMSO Control (-):0.33294999999999997±0.14942
Plate Z-Factor:-0.0674
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DBLink | Rows returned: 1
5510 N-methyl-N-(3-methylphenyl)-1-naphthalen-2-yloxy-methanethioamide

internal high similarity DBLink | Rows returned: 1
BTB 13928 1.0000

active | Cluster 1478 | Additional Members: 4 | Rows returned: 0
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