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Compound InformationSONAR Target prediction
Name:

RIFAMPIN

Unique Identifier:SPE01500529
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:
Molecular Weight:764.48 g/mol
X log p:11.905  (online calculus)
Lipinksi Failures2
TPSA106.97
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:16
Rotatable Bond Count:5
Canonical Smiles:COC1C=COC2(C)Oc3c(C)c(O)c4c(O)c(NC(=O)C(C)=CC=CC(C)C(O)C(C)C(O)C(C)C(O
C(C)=O)C1C)c(C=NN1CCN(C)CC1)c(O)c4c3C2=O
Source:semisynthetic; L-5103, Ba-41166/E, NSC-113926
Therapeutics:antibacterial (tuberculostatic)
Generic_name:RIFAMPICIN
Chemical_iupac_name:RIFAMPICIN
Drug_type:Experimental
Kegg_compound_id:C06688
Drugbank_id:EXPT02777
Logp:3.719
Cas_registry_number:13292-46-1
Drug_category:Orphan Nuclear Receptor Pxr inhibitor
Organisms_affected:-1

Found: 204 nonactive | as graph: single | with analogs [1] << Back 1 2 3 4 5 6 7 8 9 10  Next >> [204]
Species: 4932
Condition: IRE1
Replicates: 2
Raw OD Value: r im 0.8375±0.00339411
Normalized OD Score: sc h 1.0343±0.00331421
Z-Score: 1.2669±0.13902
p-Value: 0.207372
Z-Factor: -8.10963
Fitness Defect: 1.5732
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Spectrum_ED
Plate Number and Position:4|H5
Drug Concentration:50.00 nM
OD Absorbance:595 nm
Robot Temperature:30.00 Celcius
Date:2010-08-10 YYYY-MM-DD
Plate CH Control (+):0.10149999999999999±0.00740
Plate DMSO Control (-):0.94425±0.03978
Plate Z-Factor:0.8448
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DBLink | Rows returned: 0

internal high similarity DBLink | Rows returned: 0

active | Cluster 6557 | Additional Members: 7 | Rows returned: 2
Prest1296 0.411764705882353
Prest833 0

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