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Compound InformationSONAR Target prediction
Name:

PROCHLORPERAZINE EDISYLATE

Unique Identifier:SPE01500505
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:
Molecular Weight:533.903 g/mol
X log p:16.724  (online calculus)
Lipinksi Failures1
TPSA35.02
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:3
Rotatable Bond Count:4
Canonical Smiles:CN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc23)CC1.OS(=O)(=O)CCS(O)(=O)=O
Source:synthetic
Therapeutics:antiemetic, antipsychotic, treatment of vertigo

Found: 102 active | as graph: single | with analogs [1] << Back 91 92 93 94 95 96 97 98 99 100  Next >> [102]
Species: 4932
Condition: TOP1
Replicates: 2
Raw OD Value: r im 0.4399±0.0226274
Normalized OD Score: sc h 0.6425±0.0180973
Z-Score: -5.7750±0.57694
p-Value: 0.0000000403296
Z-Factor: 0.544005
Fitness Defect: 17.0262
Bioactivity Statement: Active
Experimental Conditions
Library:Spectrum
Plate Number and Position:17|B11
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:25.70 Celcius
Date:2006-04-26 YYYY-MM-DD
Plate CH Control (+):0.039900000000000005±0.00122
Plate DMSO Control (-):0.6495500000000001±0.02284
Plate Z-Factor:0.8693
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DBLink | Rows returned: 1
91499 2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine; ethane-1,2-disulfonic acid

internal high similarity DBLink | Rows returned: 0

nonactive | Cluster 6041 | Additional Members: 22 | Rows returned: 191 2 3 4 Next >> 
Prest853 0.555555555555556
LAT002B04 0.5375
SPE01500575 0.5375
Prest437 0.5375
LOPAC 00320 0.5375
SPE01503936 0.452054794520548

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